|1.||Bagrov, Alexei Y: 26 articles (11/2015 - 03/2002)|
|2.||Fedorova, Olga V: 25 articles (10/2015 - 03/2002)|
|3.||Puschett, Jules B: 13 articles (07/2015 - 09/2005)|
|4.||Shapiro, Joseph I: 12 articles (04/2014 - 12/2002)|
|5.||Malhotra, Deepak: 10 articles (04/2014 - 12/2002)|
|6.||Lakatta, Edward G: 9 articles (10/2015 - 03/2002)|
|7.||Shidyak, Amjad: 7 articles (06/2012 - 01/2007)|
|8.||Xie, Zijian: 7 articles (12/2009 - 12/2002)|
|9.||Kennedy, David J: 6 articles (11/2015 - 03/2006)|
|10.||Frolova, Elena V: 6 articles (08/2015 - 12/2007)|
07/01/2015 - "Previous studies from this laboratory have demonstrated that the bufodienolide, marinobufagenin, causes a syndrome in the pregnant rat that resembles human preeclampsia. "
08/01/2011 - "This suggests that subsequent studies on levels of marinobufagenin as a screening test for preeclampsia could be done utilizing urine samples, which are easier to obtain, less invasive, more cost-effective, and as accurate as the serological tests."
07/01/2015 - "Differing effects of resibufagenin on cinobufatalin- versus marinobufagenin-induced preeclampsia in a rodent model."
06/15/2014 - "Marinobufagenin (MBG) is a cardiotonic steroid that increases in the circulation in preeclampsia. "
04/01/2013 - "Analytical aspects of marinobufagenin and its applications in the diagnosis of preeclampsia."
08/01/2015 - "Marinobufagenin-induced vascular fibrosis is a likely target for mineralocorticoid antagonists."
04/01/2014 - "Passive immunization against marinobufagenin attenuates renal fibrosis and improves renal function in experimental renal disease."
06/01/2012 - "Monoclonal antibody against marinobufagenin reverses cardiac fibrosis in rats with chronic renal failure."
12/01/2009 - "We have observed that the cardiotonic steroid marinobufagenin plays an important role in the diastolic dysfunction and cardiac fibrosis seen with experimental renal failure. "
05/01/2009 - "The cardiotonic steroid marinobufagenin (MBG) has been implicated in the pathogenesis of experimental uremic cardiomyopathy, which is characterized by progressive cardiac fibrosis. "
|3.||Cardiomegaly (Heart Hypertrophy)
11/01/2010 - "In animal studies, partial nephrectomy induces marinobufagenin elevation, cardiac hypertrophy, and fibrosis. "
06/01/2012 - "In the present study, we tested whether a monoclonal antibody (mAb) against the bufadienolide CTS, marinobufagenin (MBG), alleviates cardiac hypertrophy and fibrosis in partially nephrectomized (PNx) rats. "
01/01/2007 - "They may have a primary role in the development of cardiac dysfunction and failure because (i) offspring of hypertensive patients evidently inherit elevated plasma concentrations of endogenous ouabain; (ii) such elevated concentrations correlate positively with cardiac dysfunction, hypertrophy, and arterial hypertension; (iii) about 40% of Europeans with uncomplicated essential hypertension show increased concentrations of endogenous ouabain associated with reduced heart rate and cardiac hypertrophy; (iv) in patients with advanced arterial hypertension, circulating levels of endogenous ouabain correlate with BP and total peripheral resistance; (v) among patients with idiopathic dilated cardiomyopathy, high circulating levels of endogenous ouabain and marinobufagenin identify those individuals who are predisposed to progressing more rapidly to heart failure, suggesting that endogenous ouabain (and marinobufagenin) may contribute to toxicity upon digoxin therapy. "
05/01/1998 - "The present study describes purification of a bufodienolide, which is similar to marinobufagenin, from the urine of patients after acute myocardial infarction with the use of thin-layer chromatography and reverse-phase high-performance liquid chromatography (HPLC). "
11/01/2010 - "Cardiotonic steroids, including marinobufagenin, are a group of new steroid hormones found in plasma and urine of patients with congestive heart failure, myocardial infarction, and chronic renal failure. "
|5.||Myocardial Ischemia (Ischemic Heart Diseases)
|2.||Adenosine Triphosphatases (ATPase)
|4.||Ouabain (G Strophanthin)
|6.||Sodium-Potassium-Exchanging ATPase (Sodium, Potassium ATPase)