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early endosome antigen 1

a hydrophilic peripheral membrane protein associated with endosomes; MW 180 kDa; GenBank L40157
Also Known As:
EEA1 protein, human; Eea1 protein, mouse; Zinc finger FYVE domain-containing protein 2, human; early endosome antigen 1, protein, human; early endosome autoantigen 1, mouse
Networked: 13 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Fritzler, Marvin J: 2 articles (01/2016 - 06/2003)
2. Costa, Susana: 1 article (01/2022)
3. Dias, Jane: 1 article (01/2022)
4. Eulalio, Ana: 1 article (01/2022)
5. Lisowski, Clivia: 1 article (01/2022)
6. Mano, Miguel: 1 article (01/2022)
7. Silva, Ricardo Jorge: 1 article (01/2022)
8. Alexandrov, Kirill: 1 article (01/2021)
9. Ariotti, Nicholas: 1 article (01/2021)
10. Ferguson, Charles: 1 article (01/2021)

Related Diseases

1. Infections
12/01/2019 - "In this study, early endosome antigen 1 (EEA1) protein that was involved in the tethering step of the vesicle and early endosome fusion was investigated during YHV infection. "
01/01/2022 - ": CDK4: cyclin dependent kinase 4; CDK6: cyclin dependent kinase 6; CDK4-CDK6i: CDK4-CDK6 inhibitor IV; cfu: colony-forming units; CHQ: chloroquine; DMSO: dimethyl sulfoxide; EEA1: early endosome antigen 1; FITC: fluorescein isothiocyanate; GFP: green fluorescent protein; hpi: hours post-infection; LAMP1: lysosomal associated membrane protein 1; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3 beta; MOI: multiplicity of infection; RAB7: RAB7, member RAS oncogene family; SCV: Salmonella-containing vacuole; SPI-1: Salmonella pathogenicity island-1; SPI-2: Salmonella pathogenicity island-2; TFEB: transcription factor EB; T3SS: type III secretion system."
01/01/2020 - "3-MA: 3-methyladenine; BafA1: bafilomycin A1; CFU: colony-forming units; DQ-BSA: dye quenched-bovine serum albumin; EEA1: early endosome antigen 1; FITC: fluorescein isothiocyanate; FM 4-64: pyridinium,4-(6-[4-{diethylamino}phenyl]-1,3,5-hexatrienyl)-1-(3[triethylammonio] propyl)-dibromide; GFP: green fluorescent protein; LAMP1: lysosomal associated membrane protein 1; MAPILC3/LC3: microtubule associated protein 1 light chain 3; MOI: multiplicity of infection; MTOR: mechanistic target of rapamycin kinase; RFP: red fluorescent protein; SCVs: Salmonella-containing vacuoles; SD: standard deviation; SDS: sodium dodecyl sulfate; SEM: standard mean error; SQSTM1: sequestosome 1; TBK1: TANK binding kinase 1; TFEB: transcription factor EB."
2. Anthrax
3. Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome)
4. Paraparesis
5. Hereditary Spastic Paraplegia

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Caveolin 1
3. Transferrin (beta 2 Transferrin)
4. Green Fluorescent Proteins
5. Microtubule-Associated Proteins (Microtubule-Associated Protein 2)
6. Transcription Factors (Transcription Factor)
7. Phosphotransferases (Kinase)
8. Red Fluorescent Protein
9. ErbB Receptors (EGF Receptor)
10. Lysosomal-Associated Membrane Protein 1