|1.||Queralt, J: 2 articles (12/2000 - 01/2000)|
|2.||Riendeau, Denis: 1 article (02/2007)|
|3.||Rudd, John A: 1 article (02/2007)|
|4.||Ngan, Man P: 1 article (02/2007)|
|5.||Sam, Tasia S W: 1 article (02/2007)|
|6.||Robichaud, Annette: 1 article (02/2007)|
|7.||Willburger, R E: 1 article (03/2005)|
|8.||Heukamp, M: 1 article (03/2005)|
|9.||Wiese, M: 1 article (03/2005)|
|10.||Dorfmüller, P: 1 article (03/2005)|
|2.||Stomach Ulcer (Gastric Ulcer)
03/01/1998 - "Thus, inhibition of chronic gastric ulcer healing by L-745,337 occurs within a potentially therapeutic dose-range. "
03/01/1998 - "4. Dose-response curves for the inhibition of chronic gastric ulcer healing by L-745,337 (administered twice daily intragastrically) showed an ID50 value of 1.7 mg (4.3 micromol) kg(-1). "
03/30/1998 - "In our chronic experimental gastric ulcer model in rats, however, delay of gastric ulcer healing with L-745,337 was comparable to that with ordinary NSAIDs. "
03/01/1998 - "Selective inhibition of PGHS-2 by L-745,337 delayed gastric ulcer healing though interference with epithelial cell proliferation, angiogenesis and maturation of granulation tissue in a potentially therapeutic dose range. "
03/01/1998 - "We assessed the cellular localization and expression of PGHS-1 and PGHS-2 during gastric ulcer healing and assessed the effects of L-745,337 on previously established cryoulcers in the rat gastric stomach. "
12/01/2000 - "The L-745,337 anti-inflammatory effective-dose-50 was 0.4 mg/kg. Maximal anti-inflammation was obtained with L-745,337 or indomethacin at doses of 5 and 1 mg/kg respectively. "
12/01/2000 - "Effect of the COX-2 selective inhibitor l-745,337 on inflammation and organ prostaglandin E2 (PGE2) levels in adjuvant arthritic rats."
08/01/1997 - "The topical effects of cyclooxygenase-2 (COX-2)-selective inhibitors, flosulide (CGP 28238), L-745,337 and SC-57,666 were examined in AA- and TPA-induced ear dermal inflammation in the mouse. "
01/01/2000 - "After 14 days of treatment, a clear dose-dependent inhibition of plantar edema was seen for both flosulide (ID50 lower than 0.1 mg/kg) and L-745,337 (ID50 = 0.4 mg/kg). "
08/01/1997 - "The doses that caused 50% inhibition in AA edema (ED50) were 2.4, 0.45 and 0.35 mg/ear for flosulide, L-745,337 and SC-57,666, respectively. "
|5.||Shoulder Impingement Syndrome (Syndrome, Shoulder Impingement)
03/01/2005 - "To compare the in vitro effects of selective COX-2 inhibitors (L-745,337, NS-398 and DFU) and of COX-unspecific diclofenac on release of PGE(2 )and 6-keto-PGF(1alpha) from inflamed bursa subacromialis tissue (IBST) obtained from a total of 35 patients with shoulder impingement syndrome (SIS). "
|1.||Cyclooxygenase 2 (Cyclooxygenase-2)
|3.||Diclofenac (SR 38)
|5.||Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)
|7.||Prostaglandins E (PGE)
|8.||Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)