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ST 899

a platelet-activating factor receptor antagonist

Also Known As:

4-N,N,N-trimethylammonium-(R)-3-isovaleroyloxybutanoic acid Z-3-(5-chlorphthalidyliden)ethyl ester bromide; ST-899

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Related Diseases

1.	Septic Shock (Toxic Shock Syndrome) 10/01/1994 - "It is suggested that ST 899 may be beneficial, in combination with current therapies, in the treatment of diseases that involve overproduction of PAF, TNF, and IFN-gamma such as septic shock." 10/01/1994 - "The effect of ST 899, a novel platelet-activating factor (PAF) receptor antagonist, on serum tumor necrosis factor (TNF), interleukin-6 (IL-6), and interferon-gamma (IFN-gamma) production as well as on lethality in an experimental endotoxin shock model was investigated in C57BL/6 mice. "
2.	Shock 10/01/1994 - "Beneficial effects of a novel platelet-activating factor receptor antagonist, ST 899, on endotoxin-induced shock in mice."

Related Drugs and Biologics

1.	Interleukin-6 (Interleukin 6)
2.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3.	Platelet Activating Factor
4.	Interferon-gamma (Interferon, gamma)
5.	Endotoxins
6.	platelet activating factor receptor

Related Therapies and Procedures

1.	Therapeutics