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indene

structure in first source

Networked: 28 relevant articles (3 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Indenes: 4
        indene: 28
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Indenes: 4
    - indene: 28

Experts

1.	Kakadiya, Rajesh: 3 articles (01/2017 - 03/2012)
2.	Lee, Te-Chang: 3 articles (01/2017 - 03/2012)
3.	Sanjiv, Kumar: 3 articles (01/2017 - 03/2012)
4.	Su, Tsann-Long: 3 articles (01/2017 - 03/2012)
5.	Suman, Sharda: 3 articles (01/2017 - 03/2012)
6.	Chen, Chi-Wei: 2 articles (01/2017 - 04/2014)
7.	Chen, Yen-Hui: 2 articles (01/2017 - 04/2014)
8.	Tala, Satishkumar: 2 articles (01/2017 - 04/2014)
9.	Wu, Ming-Hsi: 2 articles (01/2017 - 04/2014)
10.	Lee, Chul-Hoon: 2 articles (11/2012 - 03/2011)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 01/01/2017 - "Corrigendum to "PI3K Inhibition Augments the Therapeutic Efficacy of a 3a-aza-Cyclopenta[α]indene Derivative in Lung Cancer Cells [Translational Oncology 7 (2014) 256-266.e5]." 04/01/2014 - "PI3K Inhibition Augments the Therapeutic Efficacy of a 3a-aza-Cyclopenta[α]indene Derivative in Lung Cancer Cells." 04/01/2014 - "The DNA interstrand cross-linking agent BO-1509, a derivative of 3a-aza-cyclopenta[α]indene, was synthesized and combined with the phosphoinositide 3-kinase (PI3K) inhibitor LY294002 to treat human lung cancer cells. " 09/01/2007 - "In the present study, we elucidated the apoptotic mechanism of PPARgamma activation in human lung cancers by using a novel PPARgamma agonist, 1-(trans-methylimino-N-oxy)-6-(2-morpholinoethoxy)-3-phenyl-(1H-indene-2-carboxylic acid ethyl ester (KR-62980), and rosiglitazone. "
2.	Inflammation (Inflammations) 02/05/2016 - "These results suggest the suitability of indene and tetralene analogues as new chemical entities for further investigation towards the management of inflammation related diseases. " 02/05/2016 - "In an effort to evaluate novel pharmacological activity of 1-chloro-2-formyl indene and tetralene analogues possessing potential antitubercular and antistaphylococcal agents, we explored its anti-inflammatory potential against lipopolysaccharide(LPS)-induced inflammation using in-vitro and in-vivo bioassay. "
3.	Hip Osteoarthritis (Coxarthrosis) 09/01/1977 - "Sulindac (cis-5-fluoro-2-methyl-l-[(p-methyl sulfinyl)-benzylidene]-indene-3-acetic acid) is a new nonsteroidal antirheumatic drug recently evaluated in a double-blind trial of 91 patients with hip osteoarthritis. "
4.	Migraine Disorders (Migraine) 04/01/2010 - "2-[(8R)-8-(3,5-Difluorophenyl)-10-oxo-6,9-diazaspiro[4.5]dec-9-yl]-N-[(2R)-2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-5-yl]acetamide (MK-3207) represents the third CGRP receptor antagonist to display clinical efficacy in migraine trials. "
5.	Glioblastoma (Glioblastoma Multiforme) 01/01/2021 - "Finally, preliminary structure-activity relationship studies in glioblastoma and nonsmall cell lung cancer cell lines were conducted on stelletin A, revealing that the singular trans-syn-trans perhydrobenz[e]indene core is essential for the cytotoxic activity of the isomalabaricane triterpenoids."

Related Drugs and Biologics

1.	Lipopolysaccharides
2.	Sulindac (Copal)
3.	Acetic Acid (Vinegar)
4.	Esters
5.	Carboxylic Acids
6.	PPAR gamma
7.	Antirheumatic Agents (DMARD)
8.	Triterpenes
9.	Calcitonin Gene-Related Peptide Receptor Antagonists
10.	Rosiglitazone (Avandia)

Related Therapies and Procedures

1.	Precision Medicine
2.	Photochemotherapy (Photodynamic Therapy)
3.	Oral Administration