leptocarpin

isolated from Leptocarpha rivularis; structure in first source; RN given for (1aR-(1aR*,3S*,4Z,5aR*,8aR*,9R*(Z),10aR*))-isomer

Also Known As:

leptocarpin, (1aR-(1aR*,3S*,4Z,5aR*,8aR*,9R*(E),10aR*))-isomer; leptocarpin, (1aR-(1aR*,3S*,4Z,5aS*,8aR*,9S*,10aR*))-isomer

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 08/27/2017 - "BACKGROUND Leptocarpin (LTC) has drawn much attention for suppressing tumor growth or reducing inflammation. " 01/11/2023 - "rivularis flower extracts are rich in molecules with therapeutic potential, including the sesquiterpene lactone leptocarpin, which displays cytotoxic effects against various cancer types in vitro. " 12/05/2015 - "Cytotoxic and apoptotic effects of leptocarpin, a plant-derived sesquiterpene lactone, on human cancer cell lines."
2.	Osteosarcoma (Osteogenic Sarcoma) 08/27/2017 - "Leptocarpin Suppresses Proliferation, Migration, and Invasion of Human Osteosarcoma by Targeting Type-1 Insulin-Like Growth Factor Receptor (IGF-1R)."
3.	Inflammation (Inflammations) 08/27/2017 - "BACKGROUND Leptocarpin (LTC) has drawn much attention for suppressing tumor growth or reducing inflammation. "

1.	Sesquiterpenes
2.	Lactones
3.	Somatomedin Receptors (Somatomedin Receptor)