|1.||Dai, Yue: 7 articles (03/2015 - 06/2008)|
|2.||Wang, Ting: 3 articles (03/2015 - 12/2014)|
|3.||Xia, Yufeng: 3 articles (03/2015 - 11/2008)|
|4.||Gong, Zhunan: 3 articles (08/2012 - 06/2008)|
|5.||Wei, Zhifeng: 2 articles (03/2015 - 08/2012)|
|6.||Xia, Yu-Feng: 2 articles (12/2014 - 08/2014)|
|7.||Liu, Mei: 2 articles (11/2008 - 06/2008)|
|8.||Luo, Yubin: 2 articles (11/2008 - 06/2008)|
|9.||Li, Ying: 2 articles (11/2008 - 06/2008)|
|10.||Bian, Guang-Xing: 2 articles (03/2008 - 05/2007)|
|1.||Parkinsonian Disorders (Parkinsonism)
10/01/2013 - "In this study, we investigated the neuroprotective effects of madecassoside, isolated from the Chinese medicinal herb Centella asiatica, in the rat model of early phase of parkinsonism. "
10/01/2013 - "These results indicated that madecassoside was effective in recovering MPTP-induced early signs of parkinsonism via its neuroprotective effects including reversing the depletion of DA, antioxidant activity, increasing ratio of Bcl-2/Bax, increasing protein expression of BDNF."
|2.||Pulmonary Fibrosis (Hamman Rich Syndrome)
08/01/2014 - "This study aimed to explore the protective effects of madecassoside (Mad), a triterpenoid saponin isolated from Centella asiatica herbs, on experimental pulmonary fibrosis (PF) and underlying mechanisms. "
08/01/2014 - "Madecassoside ameliorates bleomycin-induced pulmonary fibrosis in mice by downregulating collagen deposition."
06/01/2009 - "The present study was undertaken to determine whether madecassoside (MA) is efficacious against collagen-induced arthritis (CIA) in mice and its possible mechanisms. "
02/01/2015 - "To explore the changes of intestinal mucosal immunity in collagen-induced arthritis rats and the impact of madecassoside on these changes. "
02/01/2015 - "[Effect of Madecassoside on Intestinal Mucosal Immunity in Collagen-Induced Arthritis Rats]."
06/01/2009 - "Madecassoside attenuates inflammatory response on collagen-induced arthritis in DBA/1 mice."
12/01/2014 - "To develop a simple and highly sensitive high performance liquid chromatography with electrospray ionization mass spectrometric (LC-ESI-MS) method for the simultaneous determination of madecassoside and its major metabolite madecassic acid in rat plasma, and compare the pharmacokinetics of the two compounds in normal and collagen-induced arthritis (CIA) rats. "
05/01/2007 - "Treatment with madecassoside (3.2, 1.6 and 0.8 mg x kg(-1)) i.v. during ischemia reperfusion injury attenuated myocardial damage, that is, characteristic of decreasing infarct size, decreasing LDH and CK release. "
05/27/2014 - "Neuroprotective effects of madecassoside against focal cerebral ischemia reperfusion injury in rats."
05/01/2007 - "[Protective effect of madecassoside against reperfusion injury after regional ischemia in rabbit heart in vivo]."
03/01/2008 - "Madecassoside (MA), one of the principle terpenoids in Centella asiatica, has shown protect effect on isolated rat hearts and isolated cardiomyocytes against reperfusion injury in our previous studies. "
03/01/2008 - "Madecassoside reduces ischemia-reperfusion injury on regional ischemia induced heart infarction in rat."
03/01/2015 - "In conclusion, madecassoside displays anti-arthritis property not by absorption into blood or by its metabolite, but through an intestine-dependent manner. "
12/01/2014 - "In normal and CIA rats, madecassoside (30 mg·kg(-1)) was orally administered for 21 consecutive days from the day of arthritis onset. "
11/01/2008 - "The present study aimed to investigate the therapeutic potential and underlying mechanisms of madecassoside on collagen II (CII)-induced arthritis (CIA) in mice. "
12/01/2014 - "The pharmacokinetic characteristics of both madecassoside and madecassic acid in rats were significantly altered by arthritis status, and the differences of pharmacokinetic parameters between arthritis and normal rats coincide with the severity of arthritis. "
11/01/2008 - "Anti-rheumatoid arthritic effect of madecassoside on type II collagen-induced arthritis in mice."
|3.||Brain-Derived Neurotrophic Factor (BDNF)
|4.||1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)
|7.||Collagen Type II (Type II Collagen)
|8.||Interleukin-10 (Interleukin 10)