HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

ABT 719

a 2-pyridone compound; a gyrase inhibitor

Also Known As:

A 816719.1; A-816719.1; ABT-719; ABT719

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Pyridones: 14
      - ABT 719: 3

Experts

1.	Ball, Greg: 1 article (01/2016)
2.	Beaver, Thomas: 1 article (01/2016)
3.	Bennett-Guerrero, Elliott: 1 article (01/2016)
4.	Chawla, Lakhmir S: 1 article (01/2016)
5.	Eldred, Ann: 1 article (01/2016)
6.	Houser, Mark T: 1 article (01/2016)
7.	Khan, Samina: 1 article (01/2016)
8.	Lee, Ho-Jin: 1 article (01/2016)
9.	McCullough, Peter A: 1 article (01/2016)
10.	Mehta, Ravindra L: 1 article (01/2016)

Related Diseases

1.	Urinary Tract Infections (Urinary Tract Infection) 10/01/1996 - "ABT-719, which represents the new 2-pyridone compound class, has promise for the treatment of urinary tract infections, as suggested by the significant efficacy seen against experimental pyelonephritis caused by E. "
2.	Pyelonephritis 10/01/1996 - "Efficacy of ABT-719, a 2-pyridone antimicrobial, against enterococci, Escherichia coli, and Pseudomonas aeruginosa in experimental murine pyelonephritis." 10/01/1996 - "ABT-719, which represents the new 2-pyridone compound class, has promise for the treatment of urinary tract infections, as suggested by the significant efficacy seen against experimental pyelonephritis caused by E. "
3.	Infections 10/01/1996 - "Therapeutic ED50s for ABT-719 against these infections were equal to or up to ten-fold lower than those for ciprofloxacin, used as a reference because of similarity in mode of action. " 04/01/1995 - "ABT-719 administered orally or subcutaneously was 4- to 10-fold more effective than ciprofloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes infections in normal mice. " 04/01/1995 - "The 50% effective doses of ABT-719 were at least threefold lower than those of ciprofloxacin for therapy of intracellular infections caused by Salmonella typhimurium or Listeria monocytogenes. "
4.	Acute Kidney Injury (Acute Renal Failure) 01/01/2016 - "ABT-719 for the Prevention of Acute Kidney Injury in Patients Undergoing High-Risk Cardiac Surgery: A Randomized Phase 2b Clinical Trial."
5.	Gram-Negative Bacterial Infections 04/01/1995 - "The racemate and R forms of ABT-719 produced similar results against gram-positive and gram-negative bacterial infections. " 04/01/1995 - "ABT-719 was equivalent in efficacy to ciprofloxacin for treatment of gram-negative bacterial infections caused by Pseudomonas aeruginosa or Escherichia coli. "

Related Drugs and Biologics

1.	2-hydroxypyridine
2.	Ciprofloxacin (Cipro)
3.	Anti-Bacterial Agents (Antibiotics)

Related Therapies and Procedures

1.	Therapeutics