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isovanillin

inhibits aldehyde oxidase

Also Known As:

iso-vanillin; isovanillin, potassium salt; Benzaldehyde, 3-hydroxy-4-methoxy-

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Aldehydes: 2153
  - Benzaldehydes: 9
    - isovanillin: 6

Experts

1.	Burgoyne, Thomas: 2 articles (09/2015 - 08/2015)
2.	Cole, Caitlin: 2 articles (09/2015 - 08/2015)
3.	Lee, Annie: 2 articles (09/2015 - 08/2015)
4.	Stehno-Bittel, Lisa: 2 articles (09/2015 - 08/2015)
5.	Zaid, Gene: 2 articles (09/2015 - 08/2015)
6.	Caseli, Luciano: 1 article (01/2019)
7.	Girola, Natália: 1 article (01/2019)
8.	Guadagnin, Rafael C: 1 article (01/2019)
9.	Machado, André C: 1 article (01/2019)
10.	Veiga, Thiago A M: 1 article (01/2019)

Related Diseases

1.	Actinic Keratosis 01/01/2023 - "The present studies further defined the biology of a novel combination of isovanillin, curcumin, and harmine in actinic keratosis cells in vitro . " 01/01/2023 - "Our data demonstrate that the unique combination of isovanillin, curcumin, and harmine represents a novel therapeutic with the potential to treat actinic keratosis in a manner different from the individual components or pairs of the components." 01/01/2023 - "A novel combination of isovanillin, curcumin, and harmine (GZ17-6.02) enhances cell death and alters signaling in actinic keratoses cells when compared to individual components and two-component combinations."
2.	Neoplasms (Cancer) 01/01/2019 - "Twenty-one isovanillin derivatives were prepared in order to evaluate their cytotoxic properties against the cancer cell lines B16F10-Nex2, HL-60, MCF-7, A2058 and HeLa. " 09/14/2015 - "Erratum to: Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice." 08/05/2015 - "Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice." 04/01/2009 - "oxyphylla and their structures were identified as: (9E)-humulene-2, 3; 6, 7-diepoxide (1), 3(12), 7(13), 9(E)-humulatriene-2, 6-diol (2), (-)-oplopanone (3), yakuchinone A (4), yakuchinone B (5), tectochrysin (6), isovanillin (7), (2E, 4E)-6-hydroxy-2, 6-dimethylhepta-2, 4-dienal (8), and the cytotoxicities of compounds 1, 3-5 on cancer cell lines, A549, HT-29 and SGC-7901, were also investigated. "
3.	Prostatic Neoplasms (Prostate Cancer) 08/05/2015 - "The number of live prostate cancer cells declined in a dose/dependent manner with a 24 h exposure to the extract at doses of 0.015 to 6.25 mg/mL. A fortified version of the extract (referred to as GZ17) that contained higher levels of isovanillin, linolenic acid and β-sitosterol had a stronger effect on the cell death rate, shifting the percentage of dead cells from 30 % to 55 % at the highest dose while the vehicle control had no effect on cell numbers. " 09/14/2015 - "Erratum to: Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice." 08/05/2015 - "Arum Palaestinum with isovanillin, linolenic acid and β-sitosterol inhibits prostate cancer spheroids and reduces the growth rate of prostate tumors in mice."
4.	Brain Neoplasms (Brain Tumor) 11/01/2022 - "Radioiodination, nasal nanoformulation and preliminary evaluation of isovanillin: A new potential brain cancer-targeting agent." 11/01/2022 - "The present investigation aimed to develop a radiopharmaceutical targeting brain cancer based on natural isovanillin. "

Related Drugs and Biologics

1.	Harmine (Telepathine)
2.	Curcumin
3.	alpha-Linolenic Acid (Linolenic Acid)
4.	gamma-sitosterol (beta-sitosterol)
5.	Radiopharmaceuticals
6.	tectochrysin
7.	yakuchinone B
8.	yakuchinone-A