polysaccharide peptide

a protein-bound peptide (21% protein) containing over 20 different amino acids and 5 different sugars, arabinose, glucose, galactose, mannose & xylose; isolated from Coriolus versicolor COV-1; effective against a number of human tumor cells in vitro; do not confuse with PSK, which is a polysaccharide-protein complex, as opposed to a polysaccharide-peptide complex

Also Known As:

Networked: 61 relevant articles (2 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Bao, Yixi: 5 articles (01/2018 - 01/2008)
2.	Sargowo, Djanggan: 4 articles (02/2021 - 05/2015)
3.	Yeung, John H K: 4 articles (03/2012 - 04/2006)
4.	Lin, Zhibin: 3 articles (01/2021 - 11/2015)
5.	Heriansyah, Teuku: 3 articles (01/2019 - 05/2015)
6.	Lin, Shuqian: 3 articles (04/2018 - 11/2015)
7.	Bao, Yi-Xi: 3 articles (08/2013 - 01/2005)
8.	Or, Penelope M Y: 3 articles (03/2012 - 08/2006)
9.	Ovianti, Nadia: 2 articles (02/2021 - 09/2018)
10.	Susilowati, Eliana: 2 articles (02/2021 - 09/2018)

Related Diseases

1.	Neoplasms (Cancer) 07/30/2004 - "The present study has made use of the S180 tumor-bearing mouse model to investigate the polysaccharopeptide, PSP, isolated from the edible mushroom Coriolus versicolor, a herbal medicine known for its anti-angiogenesis properties. " 12/01/2022 - "Its cultured mycelia extracts, namely polysaccharide peptide (PSP) as the major active component in Trametes versicolor, is widely used in eastern countries to stimulate the immune system and treat deadly cancers, including CRC. " 04/27/2010 - "Polysaccharopeptide (PSP) from Coriolus versicolor (Yunzhi) is used as a supplementary cancer treatment in Asia. " 02/23/2006 - "Ganoderma lucidum Polysaccharide Peptide (Gl-PP) has shown some effects as anti-tumors in mice and potential anti-angiogenesis. " 07/30/2004 - "Fungal polysaccharopeptide inhibits tumor angiogenesis and tumor growth in mice."
2.	Atherosclerosis 09/01/2018 - "The role of polysaccharide peptide of Ganoderma lucidum as a potent antioxidant against atherosclerosis in high risk and stable angina patients." 03/21/2022 - "The polysaccharide-peptide complex from mushroom Cordyceps militaris ameliorates atherosclerosis by modulating the lncRNA-miRNA-mRNA axis."
3.	Breast Neoplasms (Breast Cancer) 01/01/2003 - "The aim of the present study is to evaluate the anti-proliferative action of, Yunzhi, polysaccharide peptide (PSP), on breast cancer cells. " 08/01/2013 - "A study on the immunomodulation of polysaccharopeptide through the TLR4-TIRAP/MAL-MyD88 signaling pathway in PBMCs from breast cancer patients." 01/01/2005 - "Eighty-two patients with breast cancer were recruited to take Yunzhi [50 mg/kg body weight, 100% polysaccharopeptide (PSP)] and Danshen (20 mg/kg body weight) capsules every day for a total of 6 months. " 03/01/2008 - "Polysaccharopeptide enhances the anticancer activity of doxorubicin and etoposide on human breast cancer cells ZR-75-30." 11/01/2006 - "Differential control of growth, cell cycle progression, and gene expression in human estrogen receptor positive MCF-7 breast cancer cells by extracts derived from polysaccharopeptide I'm-Yunity and Danshen and their combination."
4.	Glioma (Gliomas) 04/01/2018 - "lucidum polysaccharide peptide (GL-PP) in human glioma U251 cells, which was purified from grass-cultured G. " 04/01/2018 - "Polysaccharide peptide isolated from grass-cultured Ganoderma lucidum induces anti-proliferative and pro-apoptotic effects in the human U251 glioma cell line." 01/01/2001 - "Evaluation of polysaccharopeptide effects against C6 glioma in combination with radiation." 01/01/2001 - "The major goal of this study was to determine whether polysaccharopeptide (PSP), a crude polysaccharide peptide extract derived from Coriolus versicolor, a fungus, could enhance the effects of radiation against glioma cells in culture and in xenografted tumors in vivo. "
5.	Non-alcoholic Fatty Liver Disease 01/01/2018 - "The purpose of this study was to determine whether ganoderma lucidum polysaccharide peptide (GLPP) has therapeutic effect on NAFLD. "

Related Drugs and Biologics

1.	Interleukin-2 (IL2)
2.	Long Noncoding RNA
3.	MicroRNAs (MicroRNA)
4.	Messenger RNA (mRNA)
5.	Therapeutic Uses
6.	polysaccharide peptide
7.	Polysaccharides (Glycans)
8.	Interleukin-10 (Interleukin 10)
9.	Triglycerides (Triacylglycerol)
10.	Glycopeptides

Related Therapies and Procedures

1.	Immunomodulation
2.	Drug Therapy (Chemotherapy)
3.	Therapeutics
4.	Radiotherapy
5.	Immunotherapy