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human G120R protein

a human growth hormone antagonist; results from the substitution of arginine for glycine at position 120 in native 22-kDa human growth hormone; shows somatotropin Zn-dependent agonist and antagonist activity on Nb2 cells; acts as a competitive antagonist to human growth hormone (GH) due to deficient site binding of the GH receptor
Also Known As:
G120R protein, human; (G120R)hGH protein, human; growth hormone G120R, human; hGH-G120R protein, human
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