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teucrin A

a neoclerodane diterpene from the herb Germander (Teucrium chamaedrys); structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - Clerodane Diterpenes: 48
        teucrin A: 2
  - Cyclic Hydrocarbons: 97
    - Spiro Compounds: 2
      - teucrin A: 2
Polycyclic Compounds: 6
- Spiro Compounds: 2
  - teucrin A: 2

Experts

1.	Druckova, Alexandra: 1 article (10/2006)
2.	Marnett, Lawrence J: 1 article (10/2006)

Related Diseases

1.	Obesity 10/01/2006 - "The toxicity of germander, a herb used to treat obesity, is attributed to cytochrome P450 activation of the furan ring of its major diterpenoid component (teucrin A) into a reactive metabolite capable of adducting proteins. "
2.	Necrosis 11/01/1994 - "Teucrin A was found to cause the same midzonal hepatic necrosis as observed with extracts of the powedered plant material. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Diterpenes
3.	Cytochrome P-450 Enzyme System (Cytochrome P450)
4.	furan