uniconazole

structural analog of diniconazole; RN refers to ((E)-(+-))-isomer; structure given in first source

Also Known As:

beta-((4-chlorophenyl)methylene)-alpha-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol; 1H-1,2,4-triazole-1-ethanol, beta-((4-chlorophenyl)methylene)-alpha-(1,1-dimethylethyl)-

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Triazoles: 1533
      - uniconazole: 7

Experts

1.	Van Aken, Benoit: 2 articles (01/2020 - 01/2019)
2.	Chen, Jun: 1 article (03/2022)
3.	Chen, Siyu: 1 article (03/2022)
4.	Dong, Yaqian: 1 article (03/2022)
5.	Fan, Simiao: 1 article (03/2022)
6.	Li, Yubo: 1 article (03/2022)
7.	Liu, Chunyang: 1 article (03/2022)
8.	Liu, Hui: 1 article (03/2022)
9.	Wang, Yuming: 1 article (03/2022)
10.	Xie, Lijuan: 1 article (03/2022)

Related Diseases

1.	Dwarfism 12/28/2022 - "The key pathways involved in uniconazole-induced dwarfism in banana were determined according to the overlap of KEGG annotation of differentially expressed genes and (DEGs) differential abundant metabolites (DAMs). " 12/28/2022 - "Integrated metabolomic and transcriptomic analyses of regulatory mechanisms associated with uniconazole-induced dwarfism in banana." 06/13/2014 - "GA treatment alleviated the bending and dwarfism in mutants, whereas the GA biosynthesis inhibitor, uniconazole, induced such phenotypes in wild-type plants--both in a concentration-dependent manner, indicating an important role of GA in controlling erectness of the sorghum culm. "
2.	Iron Deficiencies 01/01/2020 - "The transcriptomic profiles induced in response to the three OH-derivatives were shown, again, to be similar to those induced by inhibitors of the brassinosteroid synthesis (i.e., brassinazole, propiconazole, and uniconazole), potentially resulting in iron deficiency in exposed plants. " 01/01/2019 - "Searching an Arabidopsis microarray database (Genevestigator) revealed that, unlike the parent compound, the three OH-derivatives induced expression profiles similar to inhibitors of brassinosteroid synthesis (i.e., brassinazole, propiconazole, and uniconazole), resulting in severe iron deficiency in exposed plants. "
3.	Thymoma (Thymic Carcinoma) 04/01/2022 - "Network pharmacology and KEGG pathway analysis indicated that the thyroid endocrine disrupting effects of paclobutrazol and uniconazole may be related to V-akt murine thymoma viral oncogene homolog (Akts), mitogen-activated protein kinase (MAPKs), epidermal growth factor receptor (EGFR), Insulin-like growth factor (IGF-1), IGF-IR and V-Raf murine sarcoma viral oncogene homolog B1 (BRAF). "
4.	Sarcoma (Soft Tissue Sarcoma) 04/01/2022 - "Network pharmacology and KEGG pathway analysis indicated that the thyroid endocrine disrupting effects of paclobutrazol and uniconazole may be related to V-akt murine thymoma viral oncogene homolog (Akts), mitogen-activated protein kinase (MAPKs), epidermal growth factor receptor (EGFR), Insulin-like growth factor (IGF-1), IGF-IR and V-Raf murine sarcoma viral oncogene homolog B1 (BRAF). "
5.	Disease Susceptibility (Diathesis) 09/01/2023 - "In addition, exogenous application of GA3 and GA synthesis inhibitor uniconazole could increase disease susceptibility of Sl-lncRNA47980-overexpressing plants and the resistance of Sl-lncRNA47980-silenced plants, respectively, to P. "

Related Drugs and Biologics

1.	Brassinosteroids
2.	brassinazole
3.	propiconazole
4.	hydroxide ion
5.	ErbB Receptors (EGF Receptor)
6.	Mitogen-Activated Protein Kinases
7.	Chlorophyll
8.	Insulin-Like Peptides
9.	paclobutrazol