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LY 219703

a photoactivatable diarylsulfonylurea

Also Known As:

LY-219703; LY219703; N-(4-azidophenylsulfonyl)-N'-(4-chlorophenyl)urea

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Sulfonylurea Compounds: 35
      - LY 219703: 1
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonylurea Compounds: 35
      - LY 219703: 1

Related Diseases

1.	Colonic Neoplasms (Colon Cancer) 03/01/1995 - "Our results demonstrated that against the human colon adenocarcinoma cell line GC3/c1, LY219703 is a more potent cytotoxic agent than N-(5-indanylsulfonyl)-N'-(4-chlorophenyl)urea (Sulofenur; ISCU), whereas a subline selected for resistance to ISCU was cross-resistant to LY219703, suggesting a similar mechanism of action or resistance. "
2.	Adenocarcinoma 03/01/1995 - "Characterization of the intracellular distribution and binding in human adenocarcinoma cells of N-(4-azidophenylsulfonyl)-N'-(4-chlorophenyl)urea (LY219703), a photoaffinity analogue of the antitumor diarylsulfonylurea sulofenur."

Related Drugs and Biologics

1.	LY 219703
2.	Cytotoxins (Cytolysins)
3.	sulofenur (ISCU)