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S 14080
Also Known As:
6-benzoyl-2,3-dihydrobenzothiazole; S-14080; S14080
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiazoles: 392
S 14080: 1
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Thiazoles: 392
S 14080: 1
Related Diseases
1.
Necrosis
01/01/1995 - "
2. Post-treatment with S14080 dose-dependently antagonized the hyperalgesia induced by prostaglandin E2, bradykinin, dopamine and by the hyperalgesic cytokines reported to be released by carrageenin (tumour necrosis factor alpha, interleukin-1 and interleukin-8).
"
2.
Hyperalgesia
01/01/1995 - "
1. The oral administration of a benzothiazolinone derivative (benzoyl-6 dihydro-2,3 benzothiazole), S14080, caused dose-dependent antinociception in the rat paw pressure test, which represents a model of mechanical hyperalgesia.
"
01/01/1995 - "
3. The blockade of prostaglandin E2-induced paw hyperalgesia by oral pretreatment of the rats with S14080 was abolished by prior intraplantar administration of either naloxone or NorBNI which are non-specific and specific kappa opioid antagonists, respectively.
"
01/01/1995 - "
2. Post-treatment with S14080 dose-dependently antagonized the hyperalgesia induced by prostaglandin E2, bradykinin, dopamine and by the hyperalgesic cytokines reported to be released by carrageenin (tumour necrosis factor alpha, interleukin-1 and interleukin-8).
"
Related Drugs and Biologics
1.
Interleukin-8 (Interleukin 8)
2.
Cytokines
3.
Dinoprostone (PGE2)
4.
Prostaglandins
5.
Narcotic Antagonists (Opioid Antagonists)
6.
Naloxone (Narcan)
7.
Interleukin-1 (Interleukin 1)
8.
Dopamine (Intropin)
9.
Carrageenan
10.
Bradykinin
Related Therapies and Procedures
1.
Oral Administration