Oragen

an analog of 2',5'-oligoadenylate

Also Known As:

Oragen 0004

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

1.	Infections 02/01/1995 - "These studies were undertaken to determine the effects of Oragen 0004 (Oragen), an RNase L activating 2-5A analogue, on MHV-3 replication and induction of PCA in vitro and on the course of MHV-3 infection in susceptible BALB/cJ mice in vivo. "
2.	Massive Hepatic Necrosis 02/01/1995 - "However, Oragen failed to inhibit induction of PCA following in vitro exposure of BALB/cJ mice-derived peritoneal macrophages to MHV-3 and failed to prevent the development of fulminant hepatitis in BALB/cJ mice in vivo. "

1.	Oragen
2.	2-5A-dependent ribonuclease (RNase L)