|1.||Froehner, Stanley C: 2 articles (01/2010 - 04/2005)|
|2.||Kubista, Mikael: 1 article (01/2014)|
|3.||Dmytrenko, Lesia: 1 article (01/2014)|
|4.||Mikesova, Michaela: 1 article (01/2014)|
|5.||Kriska, Jan: 1 article (01/2014)|
|6.||Dzamba, David: 1 article (01/2014)|
|7.||Cicanic, Michal: 1 article (01/2014)|
|8.||Valihrach, Lukas: 1 article (01/2014)|
|9.||Novosadova, Vendula: 1 article (01/2014)|
|10.||Benesova, Jana: 1 article (01/2014)|
|1.||Muscular Dystrophies (Muscular Dystrophy)
09/01/1995 - "A syntrophin gene maps to mouse chromosome 8 and is not the myodystrophy gene."
10/01/2003 - "Our recent studies mapped the genetic locus for abnormal muscle (AM) of chicken with muscular dystrophy to chromosome 2q using the Kobe University (KU) resource family, and revealed the chromosome region where the AM gene is located has conserved synteny to human chromosome 8q11-24.3, where the beta-1 syntrophin (SNTB1), syndecan 2 (SDC2) and Gem GTPase (GEM) genes are located. "
10/01/2003 - "Analyses of beta-1 syntrophin, syndecan 2 and gem GTPase as candidates for chicken muscular dystrophy."
10/20/1997 - "The two PDZ proteins characterized in skeletal muscle, syntrophin and neuronal nitric oxide synthase, occur in the dystrophin complex, suggesting a role for PDZ proteins in muscular dystrophy. "
07/01/2006 - "C-terminal-truncated microdystrophin recruits dystrobrevin and syntrophin to the dystrophin-associated glycoprotein complex and reduces muscular dystrophy in symptomatic utrophin/dystrophin double-knockout mice."
01/01/2014 - "As the removal of perivascular AQP4 via the deletion of α-syntrophin was shown to delay edema formation and K(+) clearance, we aimed to elucidate the impact of α-syntrophin knockout on volume changes in individual astrocytes in situ evoked by pathological stimuli using three dimensional confocal morphometry and changes in the extracellular space volume fraction (α) in situ and in vivo in the mouse cortex employing the real-time iontophoretic method. "
11/15/2010 - "These findings suggest that SE may induce impairments of astroglial AQP4 functions via disruption of the dystrophin/α-syntrophin complex that worsen vasogenic edema. "
01/24/2008 - "In the present study, to better understand rhEPO-mediated effects on chronic astrocyte response to SCI in rat, we have used immunocytochemical methods combined with confocal and electron microscopy to investigate, 1 month after injury, the effects of a single rhEPO administration on the expression of a) aquaporin 4 (AQP4), the main astrocytic water channel implicated in edema development and resolution, and two molecules (dystrophin and syntrophin) involved in its membrane anchoring; b) glial fibrillary acidic protein (GFAP) and vimentin as markers of astrogliosis; c) chondroitin sulfate proteoglycans of the extracellular matrix which are upregulated after SCI and can inhibit axonal regeneration and influence neuronal and glial properties. "
02/01/2011 - "Co-immunoprecipitation studies in HEK293 cells showed that utrophin interacts with Na(v)1.5 via syntrophin proteins, an interaction abolished by deletion of the PDZ (PSD-95, Dlg, and Zona occludens) domain-binding motif of Na(v)1.5. "
01/01/2003 - "Comparing to the original clone (syntrophin-associated serine/threonine kinase-170), syntrophin-associated serine/threonine kinase-124 is truncated just downstream of the postsynaptic density protein-95/discs large/zona occludens-1 domain. "
|5.||Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
04/01/2005 - "beta1-Syntrophin is the predominant syntrophin isoform expressed at the muscle membrane during development, and it undergoes upregulation in response to loss of alpha1-syntrophin in Duchenne muscular dystrophy and in denervation. "
10/01/1996 - "We investigated the expression of the DAPs beta-dystroglycan, alpha-sarcoglycan, gamma-sarcoglycan and syntrophin as well as utrophin in the muscles of 13 Duchenne muscular dystrophy (DMD) carriers (with variable percentages of dystrophin-deficient fibers and with a range of clinical symptoms), 2 Becker muscular dystrophy (BMD) carriers (expressing a highly truncated protein in some fibers), 2 girls with a DMD-like phenotype, and 11 BMD carriers with almost normal dystrophin expression (reduced or patchy distribution in a few fibers only and rare dystrophin-deficient fibers). "
|3.||Proteins (Proteins, Gene)
|6.||GTP Phosphohydrolases (GTPases)
|8.||Chondroitin Sulfate Proteoglycans
|9.||Glial Fibrillary Acidic Protein