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ZCR 2060

structure given in first source

Also Known As:

2-(2-(4-(diphenylmethyl)-1-piperidinyl)ethoxy)benzoic acid maleate; ZCR-2060

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzoates: 426
        ZCR 2060: 2
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Benzoates: 426
      - ZCR 2060: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - ZCR 2060: 2

Related Diseases

1.	Inflammation (Inflammations) 11/01/1994 - "ZCR-2060 may prove useful for the treatment of allergic airway inflammation or allergic disorders, especially inflammatory cell infiltration and activation." 11/01/1994 - "These results indicate that ZCR-2060 inhibits allergic airway inflammation, and PAF-induced inflammatory cell activation in guinea-pigs. " 11/01/1994 - "Effects of ZCR-2060 on allergic airway inflammation and cell activation in guinea-pigs."
2.	Allergic Rhinitis 09/01/1994 - "The antigen-induced nasal vascular permeability increase in actively and passively sensitized rats and histamine-induced nasal vascular permeability increase in rats (allergic rhinitis model) were clearly inhibited in a dose-dependent fashion by ZCR-2060. "
3.	Rhinitis 09/01/1994 - "Antiallergic effects of ZCR-2060: effect on allergic cutaneous reactions and rhinitis models in mice and rats." 09/01/1994 - "These results suggest that ZCR-2060 has antiallergic effects on allergic cutaneous reactions and experimental rhinitis, probably due to histamine H1-receptor blockage and the inhibition of histamine release."
4.	Edema (Dropsy) 09/01/1994 - "Moreover, ZCR-2060 significantly inhibited antigen-induced anaphylactic histamine release from rat peritoneal mast cells and carrageenin-induced paw edema in rats. "

Related Drugs and Biologics

1.	Anti-Allergic Agents (Antiallergic Agents)
2.	Histamine (Histamine Dihydrochloride)
3.	Carrageenan
4.	Antigens