|1.||Hoang, Sharon: 2 articles (11/2010 - 02/2005)|
|2.||Ley, Klaus: 2 articles (11/2010 - 02/2005)|
|3.||Cominelli, Fabio: 2 articles (11/2010 - 02/2005)|
|4.||Park, Eun Jeong: 2 articles (09/2010 - 02/2008)|
|5.||Peer, Dan: 2 articles (09/2010 - 02/2008)|
|6.||Shimaoka, Motomu: 2 articles (09/2010 - 02/2008)|
|7.||Wagner, N: 2 articles (07/2002 - 06/2000)|
|8.||Wagner, Norbert: 2 articles (04/2002 - 02/2002)|
|9.||McDermott, J R: 2 articles (08/2001 - 06/2000)|
|10.||Else, K J: 2 articles (08/2001 - 06/2000)|
09/01/2010 - "The aim of this study was to investigate the possibility of imaging colitis radioimmunodetection by targeting the beta(7) integrin with a radiolabeled antibody. "
09/01/2010 - "The selective uptake of (64)Cu-labeled FIB504.64 antibody in the gut of animals with colitis suggests that integrin beta(7) may be a promising target for radioimmunodetection of this disease, which would aid diagnosis, assessment, and therapy guidance of this disease."
04/01/2010 - "Mice deficient in mucosal homing (beta7 integrin-/-), enteric microbiota (germ-free), or active for immune colitis (G alpha i2-/- CD3+ transferred into Rag-/- recipients) were studied. "
12/01/2005 - "In conclusion, the combination of CD62L and beta7 integrin is required to induce acute colitis and facilitate entry of CD4+ donor T cells in the mesenteric nodes associated with lethal GVHD in allogeneic hosts."
07/01/2002 - "These results show that beta7 integrin expression is not absolutely required for T cell localization to the intestine and colitis pathogenesis."
|2.||Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
12/01/2001 - "Identification of novel polymorphisms in the beta7 integrin gene: family-based association studies in inflammatory bowel disease."
06/01/2008 - "In the present work, we address the requirement for intestinal-specific homing molecules, the chemokine/chemokine receptor pair CCL25/CCR9 and beta7 integrin, in the pathogenesis of the CD8(+) T cell-dependent Tnf(DeltaARE) mouse model of Crohn's-like inflammatory bowel disease. "
07/01/2002 - "Utilizing two different experimental mouse models of inflammatory bowel disease (IBD), this study was undertaken to determine if beta7 integrin expression is critical for T cell localization to the intestine and colitis pathogenesis. "
12/01/2001 - "Beta 7 integrin is unlikely to be involved in the genetic susceptibility to inflammatory bowel disease, and therefore future studies on chromosome 12 should focus on other positional candidate genes."
04/10/1996 - "The abnormality of expression of integrin beta7 and other cell adhesion molecules and cytotoxic, proliferative, and aggregative responses of lymphocytes from disease mice may play important roles in the pathogenesis of this heritable inflammatory bowel disease."
06/01/2004 - "Here, we show that beta7 integrin is not essential for the control of infection in mice but that beta7-deficient neonatal mice are more susceptible during the early stages of infection."
01/01/2004 - "Surprisingly, mice markedly deficient in mucosal lymphocyte populations from beta(7) integrin deficiency resolve infection, as do CD8alpha-/- or TCR-delta-/- mice. "
06/01/2000 - "Beta7 integrin-deficient mice: delayed leukocyte recruitment and attenuated protective immunity in the small intestine during enteric helminth infection."
03/01/2001 - "The role of alpha4 and beta7 integrin chains in the intestinal mast cell hyperplasia following infection of rats with the nematode parasite Nippostrongylus brasiliensis was examined in this study. "
06/01/2000 - "We have investigated the development of intestinal inflammation and pathogen-specific protective immunity to enteric helminth infection in beta7 integrin knockout (KO) mice. "
|4.||Genetic Predisposition to Disease (Genetic Predisposition)
|3.||Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
|6.||Cell Adhesion Molecules
|10.||Integrin alpha4beta1 (VLA-4)
|1.||Hematopoietic Stem Cell Transplantation