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TGF-beta type I receptor

forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm; RefSeq NM_009370 (mouse); NM_004612 (human); NM_012775 (rat)
Also Known As:
ALK-5 protein, human; ALK-5 receptor, mouse; ALK5 protein, human; ALK5 protein, mouse; ALK5 protein, rat; Alk-5 protein, mouse; SKR4 protein, human; TGF-beta RPK; TGF-beta receptor protein kinase; TGF-beta type I receptors; TGFBR-1 protein, human; TGFBR1 protein, human; TbetaR-I kinase; Tgfbr1 protein, mouse; Tgfbr1 protein, rat; activin A receptor type II-like kinase, 53kDa, human; activin receptor-like kinase 5; activin receptor-like kinase 5, human; activin-like kinase 5 receptor, human; serine-threonine-protein kinase receptor R4; serine-threonine-protein kinase receptor R4, human; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor 1, rat; transforming growth factor, beta receptor I, human; transforming growth factor, beta receptor I, mouse
Networked: 94 relevant articles (2 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Miyazono, Kohei: 5 articles (12/2008 - 12/2002)
2. ten Dijke, Peter: 3 articles (09/2010 - 10/2004)
3. Ogawa, Hideoki: 3 articles (09/2010 - 07/2005)
4. Goumans, Marie-José: 3 articles (09/2010 - 10/2004)
5. Nakao, Atsuhito: 3 articles (09/2010 - 07/2005)
6. Murphy, Alison: 3 articles (07/2006 - 11/2004)
7. Liu, Zheng: 2 articles (06/2014 - 09/2006)
8. Pardali, Evangelia: 2 articles (09/2010 - 01/2008)
9. Katoh, Ryohei: 2 articles (09/2010 - 02/2007)
10. Hatsushika, Kyosuke: 2 articles (09/2010 - 02/2007)

Related Diseases

1. Neoplasm Metastasis (Metastasis)
2. Carcinoma (Carcinomatosis)
3. Breast Neoplasms (Breast Cancer)
4. Fibrosis (Cirrhosis)
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Phosphotransferases (Kinase)
2. enhanced green fluorescent protein
3. Transforming Growth Factor beta (TGF-beta)
4. TGF-beta type I receptor
5. transforming growth factor-beta type II receptor
6. Transforming Growth Factor beta1 (TGF beta 1)
7. Messenger RNA (mRNA)
8. Ki26894
9. Ubiquitin
10. Mitogen-Activated Protein Kinases

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Filtering Surgery
3. Homologous Transplantation (Allograft)
4. Trabeculectomy (Trabeculoplasty)
5. Oral Administration