proto-oncogene protein Pbx3

RN refers to isoform a; amino acid sequence has been determined; RefSeq NM_006195 (human), NM_016768 (mouse)

Also Known As:

PBX3 protein; PBX3 protein, human; PBX3B protein; PBX3C protein; PBX3D protein; Pbx3 protein, mouse; pre B-cell leukemia transcription factor 3 protein, mouse; pre-B-cell leukemia transcription factor 3 protein, human; proto-oncogene protein Pbx3, isoform C; proto-oncogene protein Pbx3, isoform D; proto-oncogene protein Pbx3, isoform b

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - DNA-Binding Proteins: 2009
    - Homeodomain Proteins: 350
      - proto-oncogene protein Pbx3: 3
  - Neoplasm Proteins: 2
    - Oncogene Proteins: 7793
      - Proto-Oncogene Proteins: 7
        proto-oncogene protein Pbx3: 3

Experts

1.	Alharbi, Khalid Saad: 1 article (08/2020)
2.	Alotaibi, Nasser Hadal: 1 article (08/2020)
3.	Bahman, Joob: 1 article (08/2020)
4.	Bukhari, Syed Nasir Abbas: 1 article (08/2020)
5.	Dézlla, Cristina: 1 article (08/2020)
6.	Li, Meng: 1 article (08/2020)
7.	Li, Sheng: 1 article (08/2020)
8.	Mou, Daiyong: 1 article (08/2020)
9.	Tang, Min: 1 article (08/2020)
10.	Yang, Xiaodan: 1 article (08/2020)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 07/01/2020 - "Targeted binding of miR-320a to PBX3 protein can inhibit the malignant phenotype of cells and affects the occurrence and development of melanoma."
2.	Leukemia 09/20/2023 - "CD81, CD63, Bcl-2, Bax, and pre-leukemia transcription factor 3 (PBX3) protein levels were detected using western blot assay. "
3.	Hepatocellular Carcinoma (Hepatoma) 08/01/2020 - "In summary, the PBX3 protein, which is closely linked to the stemness of hepatoma cells, does not undergo degradation by the ubiquitin-proteasome system (UPM)." 08/01/2020 - "However, when we treated hepatoma cells using the proteasome inhibitor MG132, found the levels of PBX3 protein and mRNA were significantly downregulated, suggesting that PBX3 protein is not degraded by the ubiquitin-proteasome system. "

Related Drugs and Biologics

1.	Proteasome Inhibitors
2.	Transcription Factor 3
3.	Proteasome Endopeptidase Complex (Proteasome)
4.	Ubiquitin
5.	Messenger RNA (mRNA)
6.	benzyloxycarbonylleucyl-leucyl-leucine aldehyde