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salophen

structure given in first source

Also Known As:

N,N'-bis(salicylidene)-1,2-phenylenediamine

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ding, Feng: 1 article (12/2019)
2.	He, Xiaojun: 1 article (12/2019)
3.	Li, Yahui: 1 article (12/2019)
4.	Qian, Yuna: 1 article (12/2019)
5.	Shen, Jianliang: 1 article (12/2019)
6.	Wu, Chenglin: 1 article (12/2019)
7.	Zhou, Zhihua: 1 article (12/2019)
8.	Gust, Ronald: 1 article (04/2011)
9.	Hille, Annegret: 1 article (04/2011)
10.	Kircher, Brigitte: 1 article (04/2011)

Related Diseases

1.	Neoplasms (Cancer) 12/01/2019 - "Furthermore, the biological applicability of bis-salophen probe were evaluated in various normal and cancer cell lines, results have shown that this probe is highly selective and sensitive for cancer cells. " 07/25/2023 - "The results shows that GQDs-[Fe-Salen] and GQDs-[Fe-Salophen] affect the survival of MCF7 cancer cells and, by nuclear fragmentation cause 35.77% and 19.41% of early apoptosis in cells, respectively. " 05/01/2023 - "Recent in vitro investigations of N,N'-bis(salicylidene)-1,2-phenylenediamine (SAP) iron(III) complexes substituted with alkyl (ethyl, propyl, butyl) carboxylates at position 4 in tumor and leukemia cells revealed strong cytotoxic activity. "
2.	Leukemia 05/01/2023 - "Recent in vitro investigations of N,N'-bis(salicylidene)-1,2-phenylenediamine (SAP) iron(III) complexes substituted with alkyl (ethyl, propyl, butyl) carboxylates at position 4 in tumor and leukemia cells revealed strong cytotoxic activity. " 04/01/2011 - "The activity of N,N'-bis(salicylidene)-1,2-phenylenediamine (salophene, 1), its iron(II/III) and manganese(II/III) complexes as well as rac-trans-N,N'-bis(salicylidene)-1,2-cyclohexanediamine (saldach, 2) and its respective iron(II/III) complexes was evaluated against U-937 non-Hodgkin's lymphoma and the HL-60, SUP-B15, and K-562 leukemia cell lines. "
3.	Non-Hodgkin Lymphoma (Lymphosarcoma) 04/01/2011 - "The activity of N,N'-bis(salicylidene)-1,2-phenylenediamine (salophene, 1), its iron(II/III) and manganese(II/III) complexes as well as rac-trans-N,N'-bis(salicylidene)-1,2-cyclohexanediamine (saldach, 2) and its respective iron(II/III) complexes was evaluated against U-937 non-Hodgkin's lymphoma and the HL-60, SUP-B15, and K-562 leukemia cell lines. "

Related Drugs and Biologics

1.	Iron
2.	Manganese
3.	mu-oxo N,N'- bis(salicylidene)ethylenediamine iron