|1.||Ogden, R Todd: 5 articles (02/2015 - 08/2009)|
|2.||Parsey, Ramin V: 5 articles (02/2015 - 08/2009)|
|3.||Mann, J John: 5 articles (02/2015 - 08/2009)|
|4.||Oquendo, Maria A: 5 articles (02/2015 - 08/2009)|
|5.||Sullivan, Gregory M: 4 articles (02/2015 - 08/2009)|
|6.||Wang, Shuang: 4 articles (06/2014 - 04/2007)|
|7.||Zhang, Qiao-Jun: 3 articles (04/2008 - 04/2007)|
|8.||Liu, Jian: 3 articles (04/2008 - 04/2007)|
|9.||Rusyniak, Daniel E: 2 articles (10/2015 - 11/2007)|
|10.||Zaretskaia, Maria V: 2 articles (10/2015 - 11/2007)|
03/27/2006 - "Intrathecal administration of WAY-100635 had no significant effect on pain-related behavior. "
07/01/2003 - "For example, the antagonist 5HT(1A) Way 100635 was experimented with success in animals in order to augment the efficacy of clomipramine in the treatment of chronic pain. "
10/24/2013 - "Interestingly, 19 (3 mg/kg, ip, and 30 mg/kg, po) caused significant attenuation of formalin-induced behavior in early and late phases of the mouse intradermal formalin test of pain, and this in vivo effect was reversed by the selective 5-HT1AR antagonist WAY-100635. "
10/01/2003 - "Such an inhibition was not observed when paracetamol (200 microg per rat) was intrathecally coinjected with WAY 100,635, whereas the antinociceptive action of 5-HT (50 microg per rat, intrathecally) during both phases of pain was inhibited by WAY 100,635 (intrathecally). "
03/01/2001 - "We studied the antinociceptive effect of the co-administration of clomipramine and a 5-HT(1A) antagonist (WAY 100,635) in a pain test applied in normal rats and in two models of neurogenic sustained pain (mononeuropathic and diabetic rats). "
|2.||Overactive Urinary Bladder (Overactive Bladder)
|3.||Panic Disorder (Panic Attack)
09/01/2011 - "In another test, 6b caused hypothermia in mice, which was not attenuated by WAY 100635. "
11/01/2007 - "Microinjections of 0.5 nmol of WAY 100635 into the rRP significantly attenuated DPAT (0.2 mg/kg i.p.)-elicited hypothermia. "
12/01/1999 - "8-OH-DPAT-induced hypothermia was blocked by the 5-HT(1A) antagonist WAY-100635. "
04/17/1998 - "Moreover, while having no significant effect when injected alone, (+/-)-, (-)-5-Me-8-OH-DPAT and WAY 100635 antagonized the 8-OH-DPAT-induced decrease in 5-HText in rats and hypothermia in mice. "
10/08/2015 - "The hypothermia as well as the suppression of the locomotion and the hypertension could be reversed by the blockade of 5-HT1A receptors with WAY 100635. "
|5.||Schizophrenia (Dementia Praecox)
03/01/2004 - "To investigate serotonin-1A receptors in schizophrenia and their relation to symptoms, we measured the availability of serotonin-1A receptors in patients with schizophrenia using positron emission tomography with [carbonyl-(11)C]WAY-100635. "
06/01/1997 - "Given these considerations, the [3H]WAY-100635 binding data in schizophrenia clarify two points. "
12/01/2006 - "Twenty-two medication-free individuals with schizophrenia or schizo-affective disorder and 18 healthy subjects underwent PET scans with [(11)C]WAY 100635. "
06/01/2002 - "This study examined 5-HT(1A) receptors in vivo in patients with schizophrenia using positron emission tomography and [carbonyl-(11)C]-N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexane carboxamide ([(11)C]WAY-100635). "
06/01/2011 - "Six individuals with schizophrenia underwent two PET scans with [(11)C]WAY 100635; the first while medication-free (baseline) and the second while taking the atypical antipsychotic ziprasidone (on-medication). "
|1.||5-HT1A Serotonin Receptor
|4.||Serotonin (5 Hydroxytryptamine)
|6.||Serotonin 5-HT1 Receptor Antagonists
|9.||5-Hydroxytryptophan (5 Hydroxytryptophan)