|1.||Chang, Ki Churl: 8 articles (03/2015 - 05/2002)|
|2.||Kim, Hye Jung: 6 articles (03/2015 - 03/2008)|
|3.||Yun-Choi, Hye Sook: 5 articles (12/2009 - 05/2002)|
|4.||Kim, Young Min: 4 articles (09/2014 - 08/2009)|
|5.||Lee, Jae Heun: 4 articles (03/2013 - 03/2008)|
|6.||Tsoyi, Konstantin: 3 articles (09/2014 - 12/2009)|
|7.||Seo, Han Geuk: 3 articles (12/2009 - 03/2008)|
|8.||Park, Sang Won: 2 articles (09/2014 - 03/2013)|
|9.||Park, Eun Jung: 2 articles (09/2014 - 03/2013)|
|10.||Jang, Hwa Jin: 2 articles (09/2014 - 03/2013)|
|1.||Septic Shock (Toxic Shock Syndrome)
03/01/2011 - "The purpose of this study was to investigate the potential of CKD-712 as a medicine for sepsis and to confirm its protective effects on organs in animal sepsis models. "
11/01/2013 - "(S)-1-α-Naphthylmethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD712) is noted as a drug candidate for sepsis. "
09/01/2011 - "CKD712, (S)-1-(α-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, was considered as a new effective drug candidate to sepsis, based on its anti-inflammatory activity. "
03/01/2011 - "Taken together, these results show that CKD-712 has excellent potential as an effective medicine for sepsis."
03/01/2011 - "Pretreatment with CKD-712 dose-dependently increased survival rate in a lipopolysaccharide-induced sepsis model in mice. "
12/01/2009 - "Thus CKD712 may be beneficial in the treatment of cardiovascular disorders such as atherosclerosis."
03/12/2008 - "Therefore, YS 49 has potential as a therapeutic strategy for the pathogenesis of Ang II-related vascular diseases such as hypertension and atherosclerosis, via the induction of HO-1 gene activity."
09/01/2014 - "CKD712 strongly enhances the anti-cancer effects (proliferation, invasion, and apoptosis) of paclitaxel on MDA-MB-231 cells by regulating PTEN and NF-κB activity."
09/01/2014 - "CKD712, a synthetic isoquinoline alkaloid, enhances the anti-cancer effects of paclitaxel in MDA-MB-231 cells through regulation of PTEN."
03/01/2015 - "CKD-712 suppressed MMP-9, but not MMP-2 and other NF-κB-regulated proteins involved in cancer metastasis such as VEGF. "
|1.||1- (beta- naphthylmethyl)- 6,7- dihydroxy- 1,2,3,4- tetra- hydroisoquinoline (YS 51)
|3.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|4.||Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
|6.||Pyruvic Acid (Pyruvate)
|7.||Glutamic Acid (Glutamate)