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CPLX inhibitor

a carboxyalkylamine-based metalloproteinase inhibitor; structure given in first source

Also Known As:

CPLX

Networked: 9 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - CPLX inhibitor: 9

Experts

1.	Reim, Kerstin: 2 articles (07/2021 - 08/2012)
2.	Atorf, Jenny: 1 article (07/2021)
3.	Brandstätter, Johann Helmut: 1 article (07/2021)
4.	Ehrenberg, Johanna: 1 article (07/2021)
5.	Gießl, Andreas: 1 article (07/2021)
6.	Joachimsthaler, Anneka: 1 article (07/2021)
7.	Kremers, Jan: 1 article (07/2021)
8.	Lux, Uwe Thorsten: 1 article (07/2021)
9.	Pircher, Bianca: 1 article (07/2021)
10.	Di, Xinyue: 1 article (02/2021)

Related Diseases

1.	Ganglion Cysts (Ganglion) 08/01/2012 - "In the present study, we examined the effects of the absence of Cplx 3 and Cplx 4 on ganglion cell responses. " 07/29/2021 - "In the retina, all four Cplxs are present, and while we know a lot about Cplxs 3 and 4, little is known about Cplxs 1 and 2. Here, we performed in situ hybridization experiments and bioinformatics and exploited Cplx 1 and Cplx 2 single-knockout mice combined with immunocytochemistry and light microscopy to characterize in detail the cell type and synapse-specific distribution of Cplx 1 and Cplx 2. We found that Cplx 2 and not Cplx 1 is the main isoform expressed in normal and displaced amacrine cells and ganglion cells in mouse retinae and that amacrine cells seem to operate with a single Cplx isoform at their conventional chemical synapses. "
2.	Stroke (Strokes) 08/18/2009 - "Our study suggests that PCr-Mg-CPLX might have a therapeutic role in the treatment of hereditary creatine transporter deficiency and of conditions where there is a high risk of impending stroke or cerebral ischemic damage, like high-risk transient ischemic attacks, open heart surgery, and carotid surgery."
3.	Transient Ischemic Attack 08/18/2009 - "Our study suggests that PCr-Mg-CPLX might have a therapeutic role in the treatment of hereditary creatine transporter deficiency and of conditions where there is a high risk of impending stroke or cerebral ischemic damage, like high-risk transient ischemic attacks, open heart surgery, and carotid surgery."
4.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2012 - "Reduced levels of Cplx proteins have been reported in brains of patients with neurodegenerative diseases. "
5.	Salivary Gland Calculi (Sialolithiasis) 01/01/1983 - "Ca-acidic phospholipid-phosphate complexes (CPLX) were isolated from 6 whole and 2 pooled human parotid sialoliths containing the mineral phases hydroxyapatite, whitlockite and octacalcium phosphate (ash 78 +/- 16 per cent, n = 7). "

Related Drugs and Biologics

1.	X-linked Creatine deficiency
2.	Synaptotagmins (Synaptotagmin)
3.	Fluoroquinolones
4.	Protein Isoforms (Isoforms)
5.	Durapatite (Hydroxylapatite)
6.	Proteins (Proteins, Gene)
7.	Phospholipids (Phosphatides)
8.	Phosphates (Orthophosphate)
9.	Minerals
10.	octacalcium phosphate

Related Therapies and Procedures

1.	Ventriculoperitoneal Shunt
2.	Palliative Care (Palliative Therapy)