|1.||Knöll, Ralph: 4 articles (10/2015 - 01/2002)|
|2.||Chien, Kenneth R: 4 articles (03/2010 - 01/2002)|
|3.||Hoshijima, Masahiko: 4 articles (01/2007 - 01/2002)|
|4.||Molkentin, Jeffery D: 4 articles (08/2006 - 03/2004)|
|5.||Towbin, Jeffrey A: 3 articles (12/2014 - 09/2003)|
|6.||Kraft, Theresia: 3 articles (03/2010 - 03/2003)|
|7.||Wollert, Kai C: 3 articles (10/2007 - 03/2003)|
|8.||Omens, Jeffrey H: 3 articles (04/2007 - 02/2002)|
|9.||McCulloch, Andrew D: 3 articles (04/2007 - 02/2002)|
|10.||Klevitsky, Raisa: 3 articles (08/2006 - 03/2004)|
07/27/2001 - "A genetically engineered mouse lacking the expression of the muscle LIM protein (MLP-/-) was used in this study as a model of heart failure. "
01/01/2007 - "Cardiac dysfunction and heart failure are associated with abnormalities in the subcellular distribution and amounts of oligomeric muscle LIM protein."
02/17/2006 - "Transient expression of GDF15 outside the heart by intravenous adenoviral delivery, or by direct injection of recombinant GDF15 protein, attenuated ventricular dilation and heart failure in muscle lim protein gene-targeted mice through an endocrine effect. "
02/01/2005 - "Patients with heart failure after MI have reduced LV expression levels of muscle LIM protein (MLP), a component of the sarcomeric Z-disk that is involved in the integration of stress signals in cardiomyocytes. "
01/01/2002 - "Muscle LIM protein in heart failure."
|2.||Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
04/01/2012 - "Muscle LIM protein (MLP) null mice are often used as a model for human dilated cardiomyopathy. "
09/01/2010 - "The muscle Lim protein knock-out (MLP-KO) mouse model is extensively used for studying the pathophysiology of dilated cardiomyopathy. "
08/01/2005 - "Targeted deletion of cytoskeletal muscle LIM protein (MLP) in mice consistently leads to dilated cardiomyopathy (DCM) after one or more months. "
09/01/2001 - "We used this method to characterise the growth characteristics of cardiomyocytes from MLP (muscle LIM protein) knockout mice, a mouse model for dilated cardiomyopathy. "
06/01/2001 - "Muscle LIM protein (MLP) may serve as a scaffold protein on the actin-based cytoskeleton, and mice deficient in this protein (MLPKO) have been recently reported to develop dilated cardiomyopathy. "
12/01/2007 - "The aim of this study was to elucidate the role of the AT1 receptor in disease progression in muscle LIM protein (MLP)-deficient mice, which are susceptible to heart failure because of defective function of mechanosensors in cardiomyocytes. "
01/17/2008 - "We have further investigated the muscle LIM protein knockout model of HF (MLP-/-), which closely parallels human dilated cardiomyopathy disease progression and aberrant beta-adrenergic signaling, and their betaARKct rescue. "
|4.||Heart Diseases (Heart Disease)
04/01/2007 - "Transgenic murine models of cardiac disease, such as the muscle LIM protein-deficient strain used in this study, offer populations of a reproducible phenotype that readily lend themselves to serial studies. "
03/01/2003 - "Two LIM domain containing proteins, alpha-actinin associated LIM protein (ALP) and muscle LIM protein (MLP), interact with alpha-actinin, distribute in vivo to Z-lines or costameres, respectively, and, when absent, are associated with heart disease. "
10/01/2015 - "We used cysteine and glycine-rich protein 3, a known cardiomyopathy gene, in a yeast 2-hybrid screen and identified zinc-finger and BTB domain-containing protein 17 (ZBTB17) as a novel interacting partner. "
07/01/2014 - "Mutations in cysteine and glycine-rich protein 3 (CSRP3), the gene encoding MLP, have been directly associated with human cardiomyopathies, whereas aberrant expression patterns are reported in human cardiac and skeletal muscle diseases. "
10/01/2013 - "To dissect the role of β1 vs β2-ARs in modulating MLP (Muscle LIM Protein) cardiomyopathy, we crossbred MLP-/- with β1-/- or β2-/- mice. "
03/05/2010 - "A common MLP (muscle LIM protein) variant is associated with cardiomyopathy."
10/01/2007 - "Mice with a knockout (KO) of muscle LIM protein (MLP) exhibit many morphologic and clinical features of human cardiomyopathy. "
|3.||Adrenergic Agonists (Adrenergic Receptor Agonist)
|7.||Proteins (Proteins, Gene)