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1,2- dioleoyl- glycero- 3- phospho- 5'- (2',3')- dideoxycytidine
RN given for (Z,Z)-isomer
Also Known As:
DOP-ddC; dioleoylphosphatidyl-ddC
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Pyrimidine Nucleosides: 50
Cytidine: 535
Deoxycytidine: 307
Zalcitabine: 278
1,2-dioleoyl-glycero-3-phospho-5'-(2',3')-dideoxycytidine: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Pyrimidine Nucleosides: 50
Cytidine: 535
Deoxycytidine: 307
Zalcitabine: 278
1,2-dioleoyl-glycero-3-phospho-5'-(2',3')-dideoxycytidine: 2
Deoxyribonucleosides: 34
Deoxycytidine: 307
Zalcitabine: 278
1,2-dioleoyl-glycero-3-phospho-5'-(2',3')-dideoxycytidine: 2
Dideoxynucleosides: 27
Zalcitabine: 278
1,2-dioleoyl-glycero-3-phospho-5'-(2',3')-dideoxycytidine: 2
Related Diseases
1.
HIV Infections (HIV Infection)
12/01/1994 - "
DOP-ddC, DPP-AZT, and lipid conjugates of other antiretroviral nucleosides may provide higher levels of drug over time in plasma and in lymph nodes and spleen, important reservoirs of HIV infection, and may represent an interesting alternative approach to antiviral nucleoside treatment of AIDS.
"
2.
Hepatocellular Carcinoma (Hepatoma)
05/01/1994 - "
However, in HBV-infected human hepatoma cells (2.2.15 cells), DOP-ddC was less toxic in vitro.
"
3.
Acquired Immunodeficiency Syndrome (AIDS)
12/01/1994 - "
DOP-ddC, DPP-AZT, and lipid conjugates of other antiretroviral nucleosides may provide higher levels of drug over time in plasma and in lymph nodes and spleen, important reservoirs of HIV infection, and may represent an interesting alternative approach to antiviral nucleoside treatment of AIDS.
"
Related Drugs and Biologics
1.
Nucleosides
2.
Lipids
3.
Antiviral Agents (Antivirals)