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diepoxin sigma
structure in first source
Also Known As:
SCH 49209; SCH-49209; SCH49209; Spiro(2a,6a-epoxynaphth(2,3-b)oxirene-2(1aH),2'-naphtho(1,8-de)(1,3)dioxin)-3,7(6H,7aH)-dione, 6-hydroxy-,(1aS-(1aalpha,2abeta,6alpha,6abeta,7aalpha))-
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Spiro Compounds: 2
diepoxin sigma: 1
Ethers: 242
Cyclic Ethers: 12
Epoxy Compounds: 689
diepoxin sigma: 1
Polycyclic Compounds: 6
Spiro Compounds: 2
diepoxin sigma: 1
Related Diseases
1.
Neoplasms (Cancer)
01/01/1995 - "
Sch 49209 inhibited both tumor cell invasion and cell motility to the same extent under conditions that did not cause any apparent cytotoxicity.
"
01/01/1995 - "
A novel keto-diepoxide Sch 49209 and its derivative Sch 50672, produced by the fungus Nattrassia mangiferae, inhibited tumor cell invasion through an artificial basement membrane.
"
01/01/1995 - "
Using the murine lung epidermoid carcinoma M27 cells implanted SC in mice as a model, we found both Sch 49209 and Sch 50672 inhibited the growth of this tumor at doses ranging from 2 to 10 mg/kg. These compounds also decreased the formation of spontaneous lung metastasis in this model.
"
2.
Neoplasm Metastasis (Metastasis)
01/01/1995 - "
Using the murine lung epidermoid carcinoma M27 cells implanted SC in mice as a model, we found both Sch 49209 and Sch 50672 inhibited the growth of this tumor at doses ranging from 2 to 10 mg/kg. These compounds also decreased the formation of spontaneous lung metastasis in this model.
"
3.
Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/01/1995 - "
Using the murine lung epidermoid carcinoma M27 cells implanted SC in mice as a model, we found both Sch 49209 and Sch 50672 inhibited the growth of this tumor at doses ranging from 2 to 10 mg/kg. These compounds also decreased the formation of spontaneous lung metastasis in this model.
"
Related Drugs and Biologics
1.
Sch 50672