diepoxin sigma

structure in first source

Also Known As:

SCH 49209; SCH-49209; SCH49209; Spiro(2a,6a-epoxynaphth(2,3-b)oxirene-2(1aH),2'-naphtho(1,8-de)(1,3)dioxin)-3,7(6H,7aH)-dione, 6-hydroxy-,(1aS-(1aalpha,2abeta,6alpha,6abeta,7aalpha))-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Spiro Compounds: 2
      - diepoxin sigma: 1
- Ethers: 242
  - Cyclic Ethers: 12
    - Epoxy Compounds: 689
      - diepoxin sigma: 1
Polycyclic Compounds: 6
- Spiro Compounds: 2
  - diepoxin sigma: 1

Related Diseases

1.	Neoplasms (Cancer) 01/01/1995 - "Sch 49209 inhibited both tumor cell invasion and cell motility to the same extent under conditions that did not cause any apparent cytotoxicity. " 01/01/1995 - "A novel keto-diepoxide Sch 49209 and its derivative Sch 50672, produced by the fungus Nattrassia mangiferae, inhibited tumor cell invasion through an artificial basement membrane. " 01/01/1995 - "Using the murine lung epidermoid carcinoma M27 cells implanted SC in mice as a model, we found both Sch 49209 and Sch 50672 inhibited the growth of this tumor at doses ranging from 2 to 10 mg/kg. These compounds also decreased the formation of spontaneous lung metastasis in this model. "
2.	Neoplasm Metastasis (Metastasis) 01/01/1995 - "Using the murine lung epidermoid carcinoma M27 cells implanted SC in mice as a model, we found both Sch 49209 and Sch 50672 inhibited the growth of this tumor at doses ranging from 2 to 10 mg/kg. These compounds also decreased the formation of spontaneous lung metastasis in this model. "
3.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/01/1995 - "Using the murine lung epidermoid carcinoma M27 cells implanted SC in mice as a model, we found both Sch 49209 and Sch 50672 inhibited the growth of this tumor at doses ranging from 2 to 10 mg/kg. These compounds also decreased the formation of spontaneous lung metastasis in this model. "

Related Drugs and Biologics

1.	Sch 50672