tris-sulfotyrosyl dodecapeptide-I

the primary sequence is identical to 1142-1153 sequence of the insulin proreceptor

Also Known As:

3S-peptide-I; TRDIY(S)ETDY(S)Y(S)RK-amide; TRDIYETDYYRKamide

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Insulin Resistance 01/01/1998 - "These findings provide evidence that 3S-peptide-I may improve insulin responsiveness in intact cells by inhibiting LAR, an enzyme whose activity has been implicated in the pathogenesis of insulin resistance."
2.	Hepatocellular Carcinoma (Hepatoma) 01/01/1998 - "Because of the potential role of the transmembrane PTPase LAR in the regulation of insulin signaling, we assessed the effect of 3S-peptide-I on recombinant LAR PTPase activity and in McA-RH7777 rat hepatoma cells overexpressing full-length LAR protein (McA4B/LAR). "

1.	Protein Tyrosine Phosphatases
2.	Proteins (Proteins, Gene)
3.	Insulin (Novolin)
4.	Enzymes