cereulide

05/01/2013 - "This new method will provide clinicians with an improved tool for more rapidly and quantitatively determining the presence of cereulide in food and diagnosing food poisoning caused by cereulide."
07/01/2023 - "The content of cereulide in poisoned food samples was 1287-7398 μg/kg, the content of cereulide in two raw materials cold noodles was 0.4 and 9.4 μg/kg. The method is simple, rapid, high sensitivity and accurate, and can realize the rapid treatment of food poisoning caused by cereulide."
07/01/2023 - "The detection limit of cereulide was 0.2-0.3 μg/kg, and the quantification limit was 0.5-1.0 μg/kg. The established method was applied to the detection of the actual samples causing food poisoning in a certain place in Beijing. "
07/01/2023 - "To develop a method for rapid determination of Bacillus cereus cereulide in rice and flour products by ultra-performance liquid chromatography-tandem mass spectrometry, providing emergency measures for food poisoning caused by cereulide. "
07/01/2023 - "[Rapid confirmation method of food poisoning caused by Bacillus cereus cereulide in rice and flour products]."

01/01/2018 - "Pigs were orally challenged with cereulide using single doses of 10-150 μg cereulide kg-1 body weight to study acute effects or using daily doses of 10 μg cereulide kg-1 body weight administered for 7 days to investigate effects of longtime, chronic exposure. "
08/04/2014 - "Cereulide (CER) intoxication occurs at relatively high doses of 8 µg/kg body weight. "
10/01/2003 - "Both assays showed that the poisonous food contained approximately 1.6 microg of cereulide g(-1) implying the toxic dose in human as < or =8 microg kg(-1) body weight. "
08/24/2021 - "In this study, oral administration of 50 and 200 μg/kg body weight cereulide in the mice for 28 days caused oxidative stress in liver and kidney tissues and induce abnormal expression of inflammatory factors. "
11/01/2021 - "In the study, based on mouse model, cereulide exposure (50 μg/kg body weight) for 28 days induced intestinal inflammation, gut microbiota dysbiosis and food intake reduction. "

08/24/2021 - "Cereulide is one of the main food-borne toxins for vomiting synthesized by Bacillus cereus, and it widely contaminates meat, eggs, milk, and starchy foods. "
09/01/2002 - "As the emesis causing concentration of cereulide is around 10 microg/kg of total body mass, our results suggest that emesis causing or even lower doses of cereulide may also have a systemic natural killer cell suppressive effect."
07/15/1995 - "Emesis of rhesus monkeys induced by intragastric administration with the HEp-2 vacuolation factor (cereulide) produced by Bacillus cereus."
12/01/2011 - "Even though high toxin levels were observed, to date there are no known reports on diarrhea or vomiting due to the consumption or afitin, iru and sonru in Benin, which also according to the present study is likely to be expected from the low levels of cereulide produced at 40 °C."
01/01/2022 - "Cereulide-producing Bacillus cereus, which causes foodborne illnesses with vomiting, and psychrotolerant B. "

11/01/2021 - "Chronic cereulide exposure causes intestinal inflammation and gut microbiota dysbiosis in mice."
11/01/2021 - "According to the cell models, low dose cereulide exposure disrupted the intestinal barrier function and caused intestinal inflammation, which were resulted from endoplasmic reticulum (ER) stress IRE1/XBP1/CHOP pathway activation to induce cell apoptosis and inflammatory cytokines production. "
01/01/2020 - "Combinatory effects of cereulide and deoxynivalenol on in vitro cell viability and inflammation of human Caco-2 cells."
11/01/2021 - "In the study, based on mouse model, cereulide exposure (50 μg/kg body weight) for 28 days induced intestinal inflammation, gut microbiota dysbiosis and food intake reduction. "
11/01/2021 - "In conclusion, chronic cereulide exposure induced ER stress to cause intestinal inflammation, gut microbiota dysbiosis and serotonin biosynthesis suppression. "

12/01/2011 - "Even though high toxin levels were observed, to date there are no known reports on diarrhea or vomiting due to the consumption or afitin, iru and sonru in Benin, which also according to the present study is likely to be expected from the low levels of cereulide produced at 40 °C."
01/01/2019 - "Surfactin-like emetic toxin (cereulide) and various enterotoxins including nonhemolytic enterotoxin, hemolysin BL, and cytotoxin K are responsible for food poisoning outbreaks characterized by emesis and diarrhea. "