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merodantoin
Also Known As:
1,3-dibutyl-2-thioxo-4,5-imidazolidinedione; N,N'-dibutyl-2-thio-4,5-imidazolidion
Networked:
4
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Urea: 15015
Thiourea: 362
Ethylenethiourea: 55
merodantoin: 4
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Imidazoles: 150
Imidazolidines: 39
Ethylenethiourea: 55
merodantoin: 4
Related Diseases
1.
Breast Neoplasms (Breast Cancer)
03/01/1995 - "
Growth inhibitory effects of pMC540 and merodantoin on established MCF-7 human breast tumor xenografts.
"
09/15/1994 - "
Treatment with 20 doses of merodantoin (75 mg/kg) suppressed the growth of breast tumors by 98%.
"
09/15/1994 - "
Growth inhibitory effects of merodantoin (N,N'-dibutyl-2-thio-4,5-imidazolidion) on the breast tumor growth were determined.
"
08/01/1995 - "
Relationship of mitochondrial function and cellular adenosine triphosphate levels to pMC540 and merodantoin cytotoxicity in MCF-7 human breast cancer cells.
"
03/01/1995 - "
Correlation between DNA topoisomerase II activity and cytotoxicity in pMC540 and merodantoin sensitive and resistant human breast cancer cells.
"
2.
Neoplasms (Cancer)
03/01/1995 - "
Treatment with pMC540 and merodantoin caused a 74% and 84% inhibition of tumor growth respectively.
"
03/01/1995 - "
In the absence of exogenous estradiol, identical treatment with pMC540 and merodantoin resulted in 41% and 25% inhibition of tumor growth respectively.
"
Related Drugs and Biologics
1.
merocyanine dye
2.
merocil
3.
Rhodamine 123
4.
Tamoxifen
5.
Succinate Dehydrogenase (Fumarate Reductase)
6.
Estradiol (Delestrogen)
7.
Type II DNA Topoisomerases (Topoisomerase II)
8.
DNA (Deoxyribonucleic Acid)
9.
Adenosine Triphosphate (ATP)
10.
trioctyl phosphine oxide (TOPO)
Related Therapies and Procedures
1.
Injections