vacuolar processing enzyme

converts proproteins to the corresponding mature forms in soybean; also found in castor bean, and pumpkin; see records for similar enzymes from Arabidopsis; amino acid sequence given in first source; GenBank D28876

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Cysteine Proteases: 1964
        Cysteine Endopeptidases: 4
        vacuolar processing enzyme: 6
      - Endopeptidases: 633
        Cysteine Endopeptidases: 4
        vacuolar processing enzyme: 6

Experts

1.	Bai, Suhua: 1 article (01/2022)
2.	Dong, Chaohua: 1 article (01/2022)
3.	Li, Ronghui: 1 article (01/2022)
4.	Liu, Yingshuang: 1 article (01/2022)
5.	Wang, Nan: 1 article (01/2022)
6.	Zhang, Yugang: 1 article (01/2022)
7.	Bradshaw, Corey J A: 1 article (01/2020)
8.	Li, Jia-Wei: 1 article (01/2020)
9.	Xi, Hui-Peng: 1 article (01/2020)
10.	Zhang, Jiao-Lin: 1 article (01/2020)

Related Diseases

1.	Rupture 07/20/2023 - "Involvement of Vacuolar Processing Enzyme CgVPE1 in Vacuole Rupture in the Programmed Cell Death during the Development of the Secretory Cavity in Citrus grandis 'Tomentosa' Fruits." 01/01/2018 - "Tonoplast rupture was not altered in the cathepsin B mutant and cathepsin B activation was independent of vacuolar processing enzyme (VPE). "
2.	Disease Resistance 01/01/2022 - "Apple vacuolar processing enzyme 4 is regulated by cysteine protease inhibitor and modulates fruit disease resistance."
3.	Virus Diseases (Viral Diseases) 12/01/2010 - "In one strategy, vacuolar processing enzyme (VPE) mediated the disruption of the vacuolar membrane, resulting in the release of vacuolar contents into the cytoplasm in response to viral infection. "
4.	Neoplasms (Cancer) 11/01/2019 - "Broad applicability is demonstrated by the first N-terminome analysis of sorted human primary immune cells and enriched mitochondrial fractions from pediatric cancer patients, as well as protease substrate identification from individual Arabidopsis thaliana wild type and Vacuolar Processing Enzyme-deficient mutant seedlings. "
5.	Autolysis 01/01/2020 - "The regulation of genes related to autophagy, vacuolar processing enzyme, cysteine proteases and metacaspase was involved in the final execution of cell death and autolysis. "

Related Drugs and Biologics

1.	Cysteine Proteases (Cysteine Protease)
2.	Cysteine Proteinase Inhibitors
3.	Peptide Hydrolases (Proteases)
4.	Cathepsin B