HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

19-DEJ-1 antigen

a basement membrane antigen; absent in patients with pyloric atresia-junctional epidermolysis bullosa (PA-JEB) syndrome

Also Known As:

uncein

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Biological Factors: 2472
- Antigens: 143924
  - 19-DEJ-1 antigen: 7

Related Diseases

1.	Skin Diseases (Skin Disease) 05/01/1996 - "An acquired bullous dermatosis due to an autoimmune reaction against uncein." 05/01/1996 - "This case is considered to be an acquired autoimmune bullous dermatosis due to an autoantibody reaction against uncein (19-DEJ-1 antigen), a component of anchoring filaments." 06/01/1999 - "Other acquired skin diseases of the hemidesmosomes reveal autoantibodies to a plectin-like protein, the beta4 subunit of alpha6beta4 integrin, uncein and a not yet characterized 168 kDa protein. "
2.	Bullous Pemphigoid (Pemphigoid) 05/01/1997 - "Mosaic expression of uncein and 180-kDa bullous pemphigoid antigen in generalized atrophic benign epidermolysis bullosa." 05/01/1998 - "Mosaic expression of uncein, linear IgA bullous dermatosis antigen and 180-kDa bullous pemphigoid antigen in generalized atrophic benign epidermolysis bullosa." 05/01/1997 - "Immunofluorescence microscopy of epidermodermal junction components in serial cryosections from the perilesional skin of a patient with generalized atrophic benign epidermolysis bullosa (GABEB) showed broken line-like staining of both BPAG2 (180-kDa bullous pemphigoid antigen) and uncein (antigen of 19-DEJ-1 monoclonal antibody), whereas integrin alpha 6 and laminin 5 were continuously expressed along the basement membrane zone. "
3.	Epidermolysis Bullosa 05/01/1997 - "Mosaic expression of uncein and 180-kDa bullous pemphigoid antigen in generalized atrophic benign epidermolysis bullosa." 05/01/1998 - "Mosaic expression of uncein, linear IgA bullous dermatosis antigen and 180-kDa bullous pemphigoid antigen in generalized atrophic benign epidermolysis bullosa." 05/01/1997 - "Immunofluorescence microscopy of epidermodermal junction components in serial cryosections from the perilesional skin of a patient with generalized atrophic benign epidermolysis bullosa (GABEB) showed broken line-like staining of both BPAG2 (180-kDa bullous pemphigoid antigen) and uncein (antigen of 19-DEJ-1 monoclonal antibody), whereas integrin alpha 6 and laminin 5 were continuously expressed along the basement membrane zone. "
4.	Linear IgA Bullous Dermatosis 05/01/1998 - "Mosaic expression of uncein, linear IgA bullous dermatosis antigen and 180-kDa bullous pemphigoid antigen in generalized atrophic benign epidermolysis bullosa."
5.	Epidermolysis Bullosa Dystrophica (Dystrophic Epidermolysis Bullosa) 12/01/1990 - "The expression of type VII collagen and 19-DEJ-1 antigen was examined in 73 and 71 patients, respectively, with recessive dystrophic epidermolysis bullosa (RDEB), comprising gravis, mitis, inversa, and indeterminant subsets, to better determine the specificity and sensitivity of two monoclonal antibodies directed against these dermoepidermal junction-specific epitopes. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Autoantibodies
3.	Antigens
4.	Monoclonal Antibodies
5.	Kalinin
6.	Plectin
7.	Integrin alpha6beta4
8.	Collagen Type VII
9.	Integrins
10.	Immunoglobulin A (IgA)