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SM 15178

structure in first source; leukotriene B4 antagonist

Also Known As:

SM-15178

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Ketones: 2618
  - Acetophenones: 16
    - SM 15178: 1

Related Diseases

1.	Leukopenia 04/01/1994 - "In an in vivo study, SM-15178, given orally, significantly prevented LTB4-induced transient leukopenia. "
2.	Edema (Dropsy) 04/01/1994 - "It also suppressed LTB4-induced bronchoconstriction in the guinea pig almost completely when given orally at a dose of 40 mg/kg. Furthermore, orally given SM-15178 suppressed arachidonic acid-induced neutrophil infiltration in mouse ears and Arthus reaction-induced paw edema in the mouse in a dose-dependent manner. "
3.	Arthus Reaction 04/01/1994 - "It also suppressed LTB4-induced bronchoconstriction in the guinea pig almost completely when given orally at a dose of 40 mg/kg. Furthermore, orally given SM-15178 suppressed arachidonic acid-induced neutrophil infiltration in mouse ears and Arthus reaction-induced paw edema in the mouse in a dose-dependent manner. "

Related Drugs and Biologics

1.	Arachidonic Acid (Vitamin F)