|1.||Mehlen, Patrick: 26 articles (01/2014 - 05/2002)|
|2.||Ramesh, Ganesan: 20 articles (01/2015 - 04/2008)|
|3.||Kennedy, Timothy E: 17 articles (08/2015 - 01/2002)|
|4.||Bernet, Agnès: 14 articles (12/2013 - 09/2004)|
|5.||Flores, Cecilia: 12 articles (10/2015 - 12/2007)|
|6.||Jayakumar, Calpurnia: 12 articles (01/2015 - 03/2011)|
|7.||Scoazec, Jean-Yves: 9 articles (08/2012 - 04/2003)|
|8.||Tessier-Lavigne, Marc: 8 articles (11/2015 - 05/2002)|
|9.||Lamarche-Vane, Nathalie: 8 articles (08/2015 - 04/2002)|
|10.||Eltzschig, Holger K: 7 articles (05/2015 - 02/2009)|
05/03/2012 - "Taken together, the present study shows that netrin-1 dose-dependently ameliorates spatial memory impairment and improves synaptic dysfunction as observed by recovery of population spike component of basal evoked potential and LTP in rats with global ischemia."
02/01/2015 - "The present study aimed to identify whether and how a novel protein, netrin-1, induces cardioprotection in vivo during ischemia/reperfusion (I/R) injury. "
12/01/2014 - "This study estimated the curative effects in chronic limb ischemia when MSCs allied with netrin-1. "
01/01/2014 - "The present study investigated whether pharmacological postconditoning with netrin-1 is cardioprotective against ischemia reperfusion (I/R) injury, and the underlying signaling mechanisms. "
05/03/2012 - "The present study was performed to investigate whether intrahippocampal administration of netrin-1 could improve spatial memory impairment in radial arm maze task and restore long-term potentiation (LTP) in 4-vessel occlusion model of global ischemia. "
10/15/2008 - "In the present study we tested the protective effects of netrin-1 in stroke and investigated the potential underlying mechanisms. "
08/01/2014 - "Thus, therapies targeting netrin-1 may be useful for the treatment of ischemic stroke. "
02/12/2013 - "The present study is to investigate the role of netrin-1 and its receptors in ipsilateral ventroposterior thalamic nucleus (VPN) injury secondary to stroke in hypertensive rats. "
10/01/2011 - "The aim of this study is to determine whether adeno-associated viral (AAV) mediated overexpression of netrin-1 improves post-stroke neurovascular structure and recovery of function. "
10/01/2011 - "Our results suggest that AAV mediated netrin-1 overexpression improves peri-infarct vascular density and post stroke motor function."
|3.||Diabetic Nephropathies (Diabetic Nephropathy)
01/01/2015 - "Moreover, whether netrin-1 is protective against diabetic kidney disease in a genetic model of nephropathy and in the nephropathy prone DBA background is also unknown. "
01/01/2015 - "Guidance cue netrin-1 was shown to have protective effects in diabetic nephropathy. "
09/01/2013 - "Taken together, these studies demonstrate a functional role for endogenous netrin-1 in attenuating diabetic kidney disease."
09/01/2013 - "Initial studies in wild-type mice demonstrated robust induction of renal, urinary, and plasma netrin-1 protein levels during diabetic nephropathy. "
09/01/2013 - "To study the role of netrin-1 during diabetic nephropathy, we induced diabetes in mice at the age of 8 weeks by streptocotozin (STZ) treatment. "
01/01/2014 - "Recent identification of netrin-1 as regulators of immune cell migration has led to a large number of studies looking into how netrin-1 controls inflammation and inflammatory cell migration. "
01/01/2011 - "Taking together, these studies implicate endogenous netrin-1 in attenuating renal inflammation during AKI."
06/01/2013 - "Netrin-1 regulates inflammation but the mechanism by which this occurs is unknown. "
05/01/2013 - "In addition, we hypothesized that netrin-1 could modulate colon-kidney cross talk through regulation of inflammation and apoptosis. "
04/01/2013 - "Netrin-1 guides inflammatory cell migration to control mucosal immune responses during intestinal inflammation."
|5.||Colorectal Neoplasms (Colorectal Cancer)
01/01/2010 - "In the present study, we analyzed the spatial and temporal distribution of netrin-1 and its two receptors, DCC (deleted in colorectal cancer) and UNC5B (uncoordinated-5 homolog) in human placenta using RT-PCR, Western blotting, and immunohistochemistry analysis. "
11/20/2015 - "Robo3, a Robo family member, allows commissural axons to reach and cross the spinal cord midline by antagonizing Robo1/2-mediated repulsion from midline-expressed Slits and potentiating deleted in colorectal cancer (DCC)-mediated midline attraction to Netrin-1, but without binding either Slits or Netrins. "
09/16/2015 - "Using microfluidics, we treated fluidically isolated axons of mouse primary cortical neurons with Netrin-1 and characterized axon elongation rates, as well as the membrane localization of deleted in colorectal cancer (DCC), a well-established receptor of Netrin-1. "
08/31/2015 - "During development, netrin-1 is both an attractive and repulsive axon guidance cue and mediates its attractive function through the receptor Deleted in Colorectal Cancer (DCC). "
01/20/2015 - "Deleted in colorectal cancer (DCC), a large transmembrane receptor of netrin-1, is critical for mediating netrin-1's cardioprotective function. "
|1.||Peroxisome Proliferator-Activated Receptors (PPAR)
|2.||U 0126 (UO 126)
|3.||2- phenyl- 4,4,5,5- tetramethylimidazoline- 1- oxyl- 3- oxide
|7.||Complementary DNA (cDNA)
|8.||DNA (Deoxyribonucleic Acid)
|9.||Adenosine Monophosphate (AMP)
|3.||Homologous Transplantation (Allograft)
|4.||Heterologous Transplantation (Xenotransplantation)
|5.||Drug Therapy (Chemotherapy)