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17 beta-benzoyl-4-aza-5 alpha-androst-1-ene-3-one
a 4-azasteroid; structure given in first source
Also Known As:
MK 0434; MK 434; MK-0434; MK-434
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Androstanes: 11
Androstenes: 5
Finasteride: 1561
17 beta-benzoyl-4-aza-5 alpha-androst-1-ene-3-one: 1
Heterocyclic Steroids: 4
Azasteroids: 4
Finasteride: 1561
17 beta-benzoyl-4-aza-5 alpha-androst-1-ene-3-one: 1
Experts
1.
Borst, Stephen E
: 1 article (01/2005)
2.
Conover, Christine F
: 1 article (01/2005)
3.
Lee, Jun Hak
: 1 article (01/2005)
Related Diseases
1.
Weight Loss (Weight Reduction)
01/01/2005 - "
During the second half of the study, ORX rats lost an average of 18.86 +/- 4.62 g body wt. T completely prevented weight loss, and the effect was not inhibited by MK-434 (P < 0.001).
"
2.
Bone Resorption
01/01/2005 - "
Finally, T caused a 65% decrease in urine excretion of deoxypyridinoline, a marker of bone resorption, and again the effect was not blocked by MK-434 (P < 0.0001).
"
Related Drugs and Biologics
1.
deoxypyridinoline