|1.||Rice, Kenner C: 10 articles (04/2014 - 04/2004)|
|2.||Folk, John E: 6 articles (04/2012 - 04/2004)|
|3.||Negus, S Stevens: 5 articles (04/2012 - 10/2006)|
|4.||Kieffer, Brigitte L: 4 articles (02/2015 - 01/2009)|
|5.||Matifas, Audrey: 3 articles (02/2015 - 01/2009)|
|6.||Kawaguchi, Masahiko: 3 articles (01/2008 - 07/2004)|
|7.||Sakamoto, Takanori: 3 articles (01/2008 - 07/2004)|
|8.||Horiuchi, Toshinori: 3 articles (01/2008 - 07/2004)|
|9.||Furuya, Hitoshi: 3 articles (01/2008 - 07/2004)|
|10.||Cowan, Alan: 3 articles (05/2006 - 07/2005)|
08/01/1998 - "These results suggest that SNC 80 could be useful in the treatment of pain without suppressing immune function. "
04/01/2012 - "Accordingly, this study compared SNC80 effects in complementary assays of pain-stimulated and pain-depressed behavior in rats. "
04/01/2012 - "Repeated SNC80 produced tolerance to SNC80 antinociception in a conventional assay of pain-stimulated behavior but unmasked SNC80 antinociception in an assay of pain-depressed behavior."
04/01/2012 - "The delta opioid agonist SNC80 blocked pain-related depression of intracranial self-stimulation in rats, suggesting that delta agonists may be useful to treat prodepressant effects of pain. "
04/01/2012 - "This profile suggests that SNC80 may also reverse prodepressant effects of pain. "
03/01/2001 - "SNC80 was also effective in reversing thermal hypersensitivity induced by prostaglandin E(2) (0.0158 mg) and Freund's complete adjuvant (10% concentration). "
07/01/2005 - "SNC80 exhibited a significant effect in the writhing test and limited efficacy in a model of inflammation-induced thermal hypersensitivity. "
03/01/2001 - "The effects of SNC80 and other structurally related delta-opioid receptor agonists were assessed under conditions of chemically induced hypersensitivity to thermal stimuli in four rhesus monkeys. "
01/01/2001 - "SNC 80 at 5 microM also completely abolished the wind-up and/or hypersensitivity (n=5). "
11/01/2013 - "In conclusion, intrathecal SNC80 alleviated pain hypersensitivity after peripheral inflammation in a fashion paralleling its ability to block peptide transmitter release from small peptidergic afferents, which by its pharmacology appears to represent an effect mediated by a spinal DOR. "
02/14/2009 - "However, SNC80 (1.0-10 mg/kg s.c.; 10-56 mg/kg i.p.) failed to alter ICSS frequency-rate curves at doses up to those that produced convulsions in the present study or other effects (e.g. "
02/01/2015 - "SNC80 produced dose-dependent seizure events in Ctrl mice, but these effects were not detected in Dlx-DOR mice. "
04/01/2007 - "The delta-specific agonist SNC80 decreased seizure threshold in both genotypes, wild-type and knockout. "
10/01/2006 - "In this monkey, neither behavioral convulsions nor EEG seizures were observed when a lower dose of 3.2 mg/kg was administered nine weeks later or when the same dose of 10 mg/kg SNC80 was administered one year later. "
11/01/2005 - "Slowing the rate of SNC80 administration minimized delta agonist-induced convulsions without altering the effects of SNC80 in the forced swim test. "
|2.||Oxidopamine (6 Hydroxydopamine)
|4.||delta Opioid Receptors (delta Opioid Receptor)
|5.||Morphine (MS Contin)
|6.||Analgesics (Analgesic Drugs)