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factor rXai

recombinant factor Xa with two point mutations (Asn322Ala419); a prothrombinase complex antagonist

Also Known As:

Xai factor; factor Xai; rXai factor

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Wounds and Injuries (Trauma) 10/01/1991 - "The influence of surgical trauma on factor XaI and IIaI activity and heparin concentration after a single dose of low-molecular-weight heparin."
2.	Thrombosis (Thrombus) 03/01/1994 - "At 80-100% thrombus inhibition, factor rXai and EGR-Xai had no statistically significant effect, while PPACK extended thrombin clotting time (TCT) times 2.3-fold, and heparin prolonged both activated partial thromboplastin time (APTT), prothrombin time (PT) and TCT ex-vivo clotting times 6.9-, 1.2-, and 7-fold respectively. "

Related Drugs and Biologics

1.	Heparin (Liquaemin)
2.	Thrombin
3.	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)
4.	glutamyl-glycyl-arginyl chloromethyl ketone inactivated human factor Xa
5.	phenylalanyl- prolyl- arginine- chloromethyl ketone (PPACK)