rat Ybx3 protein

RYB-a is a growth-inducible gene that encodes a protein with a conserved cold-shock domain; member of the Y-box protein family; MW 31 kDa; amino acid sequence given in first source; GenBank D28557; RefSeq NM_031979

Also Known As:

Networked: 18 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Balda, Maria S: 6 articles (12/2010 - 02/2003)
2.	Matter, Karl: 6 articles (12/2010 - 02/2003)
3.	Courtoy, Pierre J: 2 articles (05/2014 - 03/2010)
4.	Pierreux, Christophe E: 2 articles (05/2014 - 03/2010)
5.	Ali, Robin R: 2 articles (12/2010 - 03/2006)
6.	Georgiadis, Anastasios: 2 articles (12/2010 - 03/2006)
7.	Hollande, Frédéric: 2 articles (11/2007 - 12/2006)
8.	Tsapara, Anna: 2 articles (12/2006 - 03/2006)
9.	Wu, B: 1 article (05/2019)
10.	Xu, X: 1 article (05/2019)

Related Diseases

1.	Lung Injury 04/01/2018 - "The aim of the present study was to explore the regulatory effect of ZONAB on the transdifferentiation and proliferation of AECs in a model of hyperoxia‑induced lung injury. "
2.	Hyperoxia 04/01/2018 - "The present study indicated that ZONAB expression in AEC II of the BPD rats was significantly decreased from 7 days of exposure to hyperoxia onwards. " 04/01/2018 - "These results suggest that ZONAB expression in AEC II decreases under hyperoxia conditions, which promotes transdifferentiation and inhibits proliferation of AECs. " 04/01/2018 - "Decreased ZONAB expression promotes excessive transdifferentiation of alveolar epithelial cells in hyperoxia-induced bronchopulmonary dysplasia." 04/01/2018 - "The primary cells were further transfected with ZONAB plasmid or small interfering (si)RNA and then exposed to hyperoxia, and the indicators for transdifferentiation and proliferation were measured. "
3.	Neoplasms (Cancer) 05/23/2019 - "In summary, ZONAB is up-regulated in BC cell lines, which promotes invasion, demonstrating the important role it plays in tumorogenesis and cancer progression." 01/01/2016 - "Genetic and biochemical characterization of these FIP1C-proficient and -deficient tumor models revealed that FIP1C regulated E-cadherin (CDH1) trafficking and ZONAB (YBX3) function in Cdk4-mediated cell-cycle progression. " 08/14/2015 - "After demonstrating bradykinin (BK) could increase the permeability of blood-tumor barrier (BTB) via opening the tight junction (TJ), and that the possible mechanism is unclear, we demonstrated that BK could increase the expressions of eNOS and nNOS and promote ZONAB translocation into nucleus. " 01/01/2019 - "Furthermore, CM from AEP-overexpressing tumor cells suppressed endothelial ZO-1 expression, as well as ZO-1-associated nucleic acid binding protein ZONAB. " 05/23/2019 - "In order to identify the invasion-regulating function of tight junction component, we investigated the oncogenetic features of zonula occludens-1 associated nucleic acid binding protein (ZONAB), a TJ protein that is usually highly expressed in solid cancers. "
4.	Breast Neoplasms (Breast Cancer) 01/07/2008 - "New targets for breast cancer treatment were identified such as ZONAB, PACSIN3, MRP8 and SUMO1 which have human homologues. " 06/01/2014 - "We investigated the role of E2 on the expression and intracellular localization of the tight junction (TJ)-associated proteins, zonula occluden 1 (ZO-1), ZO-1-associated nucleic acid binding (ZONAB), and occludin, on the activation of c-Src and human epidermal growth factor receptor 2 (HER2) expression and cellular migration in the estrogen receptor (ER)-positive breast cancer cell lines, MCF-7 and T47D. "
5.	Reperfusion Injury 01/01/2019 - "Hypoxia-induced microRNA-191 contributes to hepatic ischemia/reperfusion injury through the ZONAB/Cyclin D1 axis."

Related Drugs and Biologics

1.	Nucleic Acids
2.	Proteins (Proteins, Gene)
3.	Carrier Proteins (Binding Protein)
4.	Occludin
5.	Cyclin D1
6.	Transcription Factors (Transcription Factor)
7.	Claudin-2
8.	Catenins
9.	Cadherins (E-Cadherin)
10.	RNA (Ribonucleic Acid)