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cinnamophilin

a lignan isolated from Cinnamomum philippinense; thromboxane receptor antagonist; structure given in first source

Networked: 8 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Wu, Tian-Shung: 5 articles (12/2021 - 08/2005)
2.	Lee, E-Jian: 4 articles (09/2021 - 08/2005)
3.	Chen, Tsung-Ying: 3 articles (05/2011 - 08/2005)
4.	Chen, Hung-Yi: 2 articles (05/2009 - 08/2005)
5.	Lee, Ming-Yang: 2 articles (05/2009 - 08/2005)
6.	Huang, Bo-Hau: 1 article (12/2021)
7.	Huang, Shih-Ya: 1 article (12/2021)
8.	Hung, Chin-Chuan: 1 article (12/2021)
9.	Lee, Tsui-Er: 1 article (12/2021)
10.	Teng, Yu-Ning: 1 article (12/2021)

Related Diseases

1.	Diaschisis 05/01/2011 - "Furthermore, cinnamophilin not only improved the ipsilateral field potentials (p < .05, respectively), but also reduced the severity of contralateral electrophysiological diaschisis (p < .05). "
2.	Ischemic Stroke 05/01/2011 - "The results suggest a need for further studies to characterize the potential of cinnamophilin in the field of ischemic stroke." 05/01/2011 - "Administration with cinnamophilin provides long-lasting neuroprotection against gray and white matter damage and improves functional and electrophysiological outcomes after ischemic stroke. " 05/01/2009 - "Cinnamophilin (CINN, (8R, 8'S)-4, 4'-dihydroxy-3, 3'-dimethoxy-7-oxo-8, 8'-neolignan) protects against ischemic stroke in mice. "
3.	Neoplasms (Cancer) 12/01/2021 - "The present study showed that cinnamophilin possesses P-gp-modulating effects and cancer MDR resensitizing ability." 12/01/2021 - "Cinnamophilin overcomes cancer multi-drug resistance via allosterically modulating human P-glycoprotein on both drug binding sites and ATPase binding sites."
4.	Brain Ischemia (Cerebral Ischemia) 05/01/2011 - "Cinnamophilin offers prolonged neuroprotection against gray and white matter damage and improves functional and electrophysiological outcomes after transient focal cerebral ischemia." 08/15/2005 - "Cinnamophilin reduces oxidative damage and protects against transient focal cerebral ischemia in mice." 05/01/2009 - "Therapeutic window for cinnamophilin following oxygen-glucose deprivation and transient focal cerebral ischemia."
5.	Atherosclerosis 09/01/1995 - "Since cinnamophilin inhibits TPreceptor-mediated VSMC proliferation, it may thus hold promising potential for the prevention of atherosclerosis or vascular diseases."

Related Drugs and Biologics

1.	Prostaglandin H2 Thromboxane A2 Receptors
2.	Member 1 Subfamily B ATP Binding Cassette Transporter
3.	Free Radical Scavengers
4.	Thromboxanes
5.	Thromboxane A2 (A2, Thromboxane)
6.	Superoxide Dismutase
7.	Oxygen (Dioxygen)
8.	Glucose (Dextrose)
9.	Catalase
10.	Adenosine Triphosphatases (ATPase)