anacardic acid

isolated from Anacardium occidentale; monophenol monooxygenase inhibitor

Also Known As:

2-hydroxy-6-pendadecylbenzoic acid; 6-(8(Z),11(Z),14-pentadecatrienyl)salicylic acid; 6-(8,11,14-pentadecatrienyl)salicylic acid; 6-nonadecyl salicylic acid; 6-pentadecyl salicylic acid; 6-pentadecylsalicylic acid

Networked: 77 relevant articles (4 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Hydroxybenzoates: 18
        Salicylates: 2339
        Anacardic Acids: 11
        anacardic acid: 77

Experts

1.	Peng, Chang: 5 articles (09/2021 - 06/2015)
2.	Luo, Xiaomei: 4 articles (09/2021 - 03/2017)
3.	Klinge, Carolyn M: 4 articles (01/2018 - 03/2010)
4.	Schultz, David J: 4 articles (01/2018 - 03/2010)
5.	Peng, Bohui: 3 articles (09/2021 - 01/2019)
6.	Jain, Sanyog: 3 articles (01/2019 - 01/2018)
7.	Kushwah, Varun: 3 articles (01/2019 - 01/2018)
8.	Alizadeh-Rad, Negin: 3 articles (01/2018 - 11/2016)
9.	He, Leye: 3 articles (09/2017 - 12/2012)
10.	Jiang, Xianzhen: 3 articles (09/2017 - 12/2012)

Related Diseases

1.	Neoplasms (Cancer) 05/01/2016 - "Combinatorial treatment with anacardic acid followed by TRAIL augments induction of apoptosis in TRAIL resistant cancer cells by the regulation of p53, MAPK and NFκβ pathways." 03/01/2014 - "Anacardic acid (AA, 2-hydroxy-6-pentadecylbenzoic acid), a constituent of the cashew-nut shell, has a variety of beneficial effects on the treatment of cancer and tumors. " 11/01/2011 - "Of note, when anacardic acid (2 mg/kg per day) was subcutaneously administrated to mice bearing human prostate tumor xenografts (n = 6-7), the volume and weight of solid tumors were significantly retarded. " 11/01/2011 - "Here, we postulate that anacardic acid affects multiple steps of tumor angiogenesis to contribute to tumor inhibition. " 09/01/2007 - "Starting from the natural product lead HATi anacardic acid, a series of 28 analogues was synthesized and investigated for HAT-inhibitory properties and effects on cancer cell growth. "
2.	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/01/2021 - "Results showed that anacardic acid moeno was able to prevent changes in lung function and preserve its mechanical properties from containing inflammatory cell infiltrate, collapse of alveoli, and decreased airway resistance, suggesting that this compound may be effective in preventing the acute respiratory distress syndrome caused by viral pathogens. " 01/01/2021 - "Effects of Anacardic Acid Monoene on the Respiratory System of Mice Submitted to Acute Respiratory Distress Syndrome." 01/01/2021 - "The present study seeks to investigate the effects of anacardic acid monoene on acute respiratory distress syndrome caused by lipopolysaccharides. "
3.	Encephalitis (Encephalitis, Rasmussen) 01/01/2020 - "In vivo, treatment of with anacardic acid in doses which ranged from 0.025 mg/kg to 2.5 mg/kg, improved pathologic scores in experimental allergic encephalitis (EAE) and in the cuprizone model of demyelination/remyelination. "
4.	Demyelinating Diseases (Demyelinating Disease) 01/01/2020 - "In vivo, treatment of with anacardic acid in doses which ranged from 0.025 mg/kg to 2.5 mg/kg, improved pathologic scores in experimental allergic encephalitis (EAE) and in the cuprizone model of demyelination/remyelination. "
5.	Experimental Arthritis 11/01/2018 - "Anacardic acid suppresses fibroblast-like synoviocyte proliferation and invasion and ameliorates collagen-induced arthritis in a mouse model." 11/01/2018 - "We explored the effects of anacardic acid on collagen-induced arthritis (CIA) in mice and on the proliferation and invasion of RA fibroblast-like synoviocytes (RA-FLSs). "

Related Drugs and Biologics

1.	Member 1 Subfamily B ATP Binding Cassette Transporter
2.	Cuprizone
3.	licochalcone A
4.	Mitoxantrone (Novantrone)
5.	Histone Acetyltransferases (Histone Acetyltransferase)
6.	Phytochemicals
7.	Salicylic Acid (2 Hydroxybenzoic Acid)
8.	Phenylephrine (Neo-Synephrine)
9.	Curcumin
10.	garcinol

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Radiotherapy
3.	Therapeutics
4.	Traditional Medicine (Folk Remedies)
5.	Catheters