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N-benzyloxycarbonylglycine

structure given in first source

Also Known As:

Cbz-Gly; N-carbobenzoxyglycine; Z-Gly

Networked: 9 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Glycine: 5151
    - N-benzyloxycarbonylglycine: 9

Experts

1.	Hu, Xinping: 1 article (12/2021)
2.	Jin, Yao: 1 article (12/2021)
3.	Liu, Qi: 1 article (12/2021)
4.	Liu, Yan: 1 article (12/2021)
5.	Ma, Yining: 1 article (12/2021)
6.	Wang, Leqi: 1 article (12/2021)
7.	Zhou, Chuhang: 1 article (12/2021)
8.	Zhou, Yuanhang: 1 article (12/2021)
9.	Cai, Shaohui: 1 article (11/2017)
10.	Huang, Sichao: 1 article (11/2017)

Related Diseases

1.	Neoplasms (Cancer) 11/15/2017 - "In this study, we demonstrated the anti-tumor activity of a novel targeting drug formed by conjugating epirubicin (EPI) with an FAPα-specific dipeptide (Z-Gly-Pro) and named it Z-GP-EPI. " 11/15/2017 - "A novel FAPα-based Z-Gly-Pro epirubicin prodrug for improving tumor-targeting chemotherapy." 12/13/2021 - "Here, we fabricated the substrate Z-Gly-Pro of fibroblast activation protein α (FAPα) and folic acid-codecorated pH-responsive polymeric micelles (dual ligand-modified PEOz-PLA polymeric micelles, DL-PP-PMs) that possessed nanodrill and tumor cell-targeted functions based on Z-Gly-pro-conjugated poly(2-ethyl-2-oxazoline)-poly(D,l-lactide) (ZGP-PEOz-PLA), folic acid (FA)-conjugated PEOz-PLA (FA-PEOz-PLA), and PEOz-PLA for cancer therapy. "
2.	Skin Mastocytoma 01/01/1988 - "The best substrate was Z-Gly-Pro-Arg-MNA giving the strongest red azo dye when incubation time was 15, 30 or 60 min. These results show the localization of human skin tryptase in dermal mast cells and the usefulness of Z-Gly-Pro-Arg-MNA as a suitable substrate tested for enzyme-histochemical localization of mast cells in healthy or mastocytoma skin."
3.	Mastocytoma 05/01/1982 - "Bioactive primary and secondary amines, when acylated with the Z-Gly-Phe group, are transported into pinocytic cells, such as macrophages, P-815 mastocytoma, SV-40 3T3, and leukemia 1210, much faster than the parent compounds. "
4.	Weight Loss (Weight Reduction) 07/13/2009 - "The Z-Gly-polyrotaxane conjugate showed a remarkable exotherm at 334 °C, together with a large weight loss. "
5.	Periodontitis 05/01/1990 - "Assays with discs impregnated with MeOSuc-Ala-Ala-Pro-Val-AFC, Z-Gly-Gly-Arg-AFC and Ala-Pro-AFC for elastase-, trypsin-, and dipeptidyl peptidase (DPP) IV-like activities respectively were evaluated using purified DPP IV and 100 eluates of crevicular fluid collected on filter paper strips from 10 gingivitis and periodontitis patients. "

Related Drugs and Biologics

1.	Epirubicin (Ellence)
2.	Dipeptides
3.	prolylarginine
4.	Cathepsin L
5.	Cathepsin K
6.	Tryptases (Tryptase)
7.	Trypsin
8.	Proteins (Proteins, Gene)
9.	Prodrugs
10.	Peptides (Polypeptides)

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)