anti-endothelial cell antibody

01/01/2006 - "To search for correlations between intima-media thickness (IMT) and high titer of AECA in patients with systemic lupus erythematosus (SLE). "
07/01/2005 - "AECA isolated from patients with active systemic lupus erythematosus (SLE) were incubated with human umbilical vein endothelial cells (HUVECs). "
10/01/1997 - "In several diseases such as systemic lupus erythematosus and systemic vasculitis, high AECA titers are found during active disease whereas lower titers or disappearence of AECA have been reported during remission. "
04/01/1998 - "The eventual pathogenic role of AECA's is less clear, with the possible exception of rheumatoid arthritis and systemic lupus erythematosus. "
01/01/2016 - "Anti-endothelial cell antibodies (AECA) are frequently detected in patients with systemic lupus erythematosus (SLE), but their pathological role remains unclear. "

02/01/2007 - "The strong correlations of AECA and anti-endothelial activity with lupus nephritis activity support an endothelial origin for renal complications in Taiwanese SLE patients."
02/01/2007 - "Significantly higher AECA (p<0.001) and anti-endothelial activities (p<0.001) were found in sera from patients with lupus nephritis compared with that from stable SLE patients or controls. "
01/01/1999 - "These results suggested that lupus nephritis patients with AECA showed a complex autoimmune disorder and provided an indirect evidence that AECA might contribute to the pathogenesis of lupus nephritis."
11/01/1993 - "These data provide indirect support for a pathogenic role for AECA in lupus nephritis."
11/01/1993 - "AECA were therefore present in most patients with acute lupus nephritis and were associated with histological evidence of active renal injury and serological evidence of endothelial cell dysfunction. "

02/01/2017 - "Thus, AECA measurement cannot be considered a diagnostic tool, but the detection and titers of AECAs are associated with disease activity in various systemic vasculitis diseases. "
01/01/2011 - "Furthermore, we discuss the possible significance of AECA in the pathophysiology of vascular damage and the value of AECA in systemic vasculitis. "
12/01/2005 - "But AECA could also be found in other systemic vasculitis and SLE."
10/02/2004 - "Prevalence of AECA in systemic vasculitis is high. "
10/02/2004 - "With either EA.hy926 or HMEC-1 as substrates, the AECA prevalence rates of systemic vasculitis (respectively 33.61% and 37.70%) were significantly higher than those of the normal and RA groups (less than 10%), and the prevalence of AECA in SLE (61.75%) was higher than that of systemic vasculitis (37.70%) when using HMEC-1 as substrates. "

10/01/2000 - "Significantly higher AECA levels were found in five patients with active disease and nephritis than in five patients with clinically inactive disease. "
08/01/1991 - "The presence of AECA conferred a positive predictive value of 0.68 for the presence of nephritis. "
08/01/1991 - "Twenty-five patients had active vasculitis at the time of assay and the highest AECA values were seen in patients with both nephritis and vasculitis. "
12/01/2013 - "Furthermore, IgG of AECA-positive SLE nephritis patients induced a marked decrease in cell index as assessed by RT-CES™ technology. "
12/01/2013 - "AECA-positive PAH patients, in contrast to SLE nephritis patients, do not have circulating IgG AECA that enhances apoptosis of HUVECs in vitro. "

10/01/1999 - "The aim of the study was to determine the prevalence of AECA in HCV patients with or without MC-associated vasculitis, and to identify associations with clinical, immunological, virological and liver characteristics. "
06/15/1996 - "The aim of this study focused on the utilization of this technique to induce the production of anti-endothelial cells Abs (AECA) and autoimmune vasculitis in a murine model. "
01/01/2019 - "The notion of KD consisting of subtypes, the major one of which is AECA-associated vasculitis, will help improve our understanding of KD and further promote early and accurate diagnosis, which remains challenging."
01/01/2018 - "Previous work has shown that AECA are abundant in other forms of vasculitis. "
01/01/2010 - "It has been reported that AECA were detected frequently in patients with vasculitis and were associated with disease activity and vasculitis symptoms. "