|1.||Chen, Wen-Tien: 12 articles (05/2015 - 08/2002)|
|2.||Mitsumata, Masako: 6 articles (10/2006 - 01/2003)|
|3.||Yamane, Tetsu: 4 articles (10/2006 - 01/2003)|
|4.||Okada, Kyoko: 4 articles (09/2005 - 01/2003)|
|5.||Jin, Xin: 4 articles (09/2005 - 01/2003)|
|6.||Iwasa, Satoshi: 4 articles (09/2005 - 01/2003)|
|7.||Ooi, Akishi: 4 articles (09/2005 - 01/2003)|
|8.||Dong, Huan: 3 articles (05/2015 - 08/2002)|
|9.||Kennedy, Alanna: 3 articles (01/2009 - 10/2006)|
|10.||Puri, Christina: 3 articles (07/2008 - 01/2005)|
12/01/2010 - "Increased expression of fibroblast activation protein-alpha in keloid fibroblasts: implications for development of a novel treatment option."
12/01/2010 - "Fibroblast activation protein alpha (FAP-α) and dipeptidyl peptidase IV (DPPIV) are proteases located at the plasma membrane promoting cell invasiveness and tumor growth and have been previously associated with keloid scars. "
07/15/2008 - "The present study was undertaken to determine the antitumor effects of an antibody-conjugate against fibroblast activation protein-alpha, a cell surface protease of activated tumor fibroblasts. "
10/01/2015 - "Fibroblast activation protein alpha (FAPα) is a cell surface protease expressed by cancer-associated fibroblasts in the microenvironment of most solid tumors. "
05/01/2015 - "Molecular and microscopic analyses were used to identify seprase and CD44 as tumor progenitor (TP) markers. "
04/01/2015 - "Fibroblast activation protein alpha (FAP) is overexpressed by fibroblasts present in the microenvironment of many tumors. "
07/28/2014 - "The reactive tumor stroma consists of a large number of myofibroblasts, characterized by high expression of fibroblast activation protein alpha (FAP). "
07/01/2007 - "Immunohistochemical studies demonstrated that the three fibroblast activation markers (FAPalpha, Tn-C, alpha-SMA) are consistently expressed in the peritumoral and intratumoral stromal compartment of medullary thyroid carcinomas and expression of FAPalpha and Tn-C correlated with the degree of desmoplasia determined histologically (p=0.001 for FAPalpha and p<0.001 for Tn-C). "
04/20/2007 - "The objective of the current study was to evaluate the expression of seprase in effusions from patients with epithelial ovarian carcinoma and its clinical values. "
01/01/2011 - "Expression and role of fibroblast activation protein-alpha in microinvasive breast carcinoma."
01/01/2008 - "No significant associations between seprase and clinicopathological features either in dysplasia or in carcinomas were found. "
04/20/2007 - "The expression of seprase protein was predominant in cytoplasm of carcinoma cells. "
|5.||Melanoma (Melanoma, Malignant)
03/21/1997 - "We have isolated seprase from cell membranes and shed vesicles of LOX human melanoma cells. "
11/01/1994 - "A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells."
05/30/2014 - "To examine the transcriptional regulation of the gene, we cloned the human seprase promoter and demonstrated that endogenous seprase expression and exogenous seprase promoter activity are high in invasive melanoma cells but not in non-invasive melanoma cells/primary melanocytes. "
05/30/2014 - "Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-β signaling."
09/01/1998 - "The increased cell surface expression of the serine integral membrane protease, seprase, has been associated with the invasive behavior of human melanoma cell lines in vitro. "
|1.||fibroblast activation protein alpha
|2.||Peptide Hydrolases (Proteases)
|3.||Urokinase-Type Plasminogen Activator (Urokinase)
|5.||Messenger RNA (mRNA)
|6.||Urokinase Plasminogen Activator Receptors
|7.||Biological Tumor Markers (Tumor Markers)
|8.||Plasminogen Activators (Plasminogen Activator)
|10.||Serine Proteases (Serine Protease)
|1.||Heterologous Transplantation (Xenotransplantation)