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phthalmustine
structure given in first source
Also Known As:
N,N-bis(2-chloroethyl)-2-phthalimidoethylamine; 1H-Isoindole-1,3(2H)-dione, 2-(2-(bis(2-chloroethyl)amino)ethyl)-
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Halogenated Hydrocarbons: 42
Mustard Compounds: 3
Nitrogen Mustard Compounds: 2
phthalmustine: 2
Carboxylic Acids: 973
Carbocyclic Acids
Phthalic Acids: 1
Phthalimides: 12
phthalmustine: 2
Imides: 79
Phthalimides: 12
phthalmustine: 2
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Isoindoles: 18
Phthalimides: 12
phthalmustine: 2
Related Diseases
1.
Neoplasms (Cancer)
01/01/1996 - "
The results indicate that phthalmustine induces marked inhibition of tumor growth and substantially prolongs host survival having curative effect while it does not adversely affect hematopoiesis at the optimum dose tested.
"
01/01/1996 - "
The hematological changes associated with the application of phthalmustine were also evaluated in tumor bearing as well as in normal male Swiss mice.
"
01/01/1994 - "
The anticancer property of phthalmustine, a hitherto unknown compound containing N-mustard attached to the phthalimide ethyl chain was evaluated using a murine tumor model.
"
2.
Carcinoma (Carcinomatosis)
01/01/1996 - "
The antitumor activity of phthalmustine (Neoplasma, 41, 1994, 35) has been evaluated in murine Ehrlich ascites carcinoma (EAC) and sarcoma-180 (S-180).
"
3.
Ascites
01/01/1996 - "
The antitumor activity of phthalmustine (Neoplasma, 41, 1994, 35) has been evaluated in murine Ehrlich ascites carcinoma (EAC) and sarcoma-180 (S-180).
"
Related Drugs and Biologics
1.
phthalimide