|1.||Shimazui, Toru: 3 articles (05/2006 - 10/2003)|
|2.||Akaza, Hideyuki: 3 articles (05/2006 - 10/2003)|
|3.||Passebosc-Faure, Karine: 2 articles (01/2005 - 12/2003)|
|4.||Tostain, Jacques: 2 articles (01/2005 - 12/2003)|
|5.||Gentil-Perret, Anne: 2 articles (01/2005 - 12/2003)|
|6.||Lambert, Claude: 2 articles (01/2005 - 12/2003)|
|7.||Li, Guorong: 2 articles (01/2005 - 12/2003)|
|8.||Genin, Christian: 2 articles (01/2005 - 12/2003)|
|9.||Yoshikawa, Kazuhiro: 2 articles (09/2004 - 10/2003)|
|10.||Saga, Shinsuke: 2 articles (09/2004 - 10/2003)|
|1.||Renal Cell Carcinoma (Grawitz Tumor)
01/01/2004 - "In our prospective analysis the pattern of cadherin-6 expression correlated with known prognostic factors of renal cell cancer on univariate and multivariate analysis. "
01/01/2004 - "Cadherin-6, a new cell adhesion molecule of the cadherin family, is specifically expressed in the proximal tubule of normal kidneys and in renal cell cancer. "
01/01/2004 - "We developed a relative risk factor for renal cell cancer for our patients using the multivariate proportional hazard Cox model, which showed a statistically significant correlation with cadherin-6 expression (p = 0.028). "
01/01/2004 - "Cadherin-6 expression in renal cell cancer correlated with known prognostic factors, such as pT stage (p = 0.03), pN stage (p = 0.001), histological growth pattern (p = 0.001), M stage (p = 0.06) and renal venous involvement (p = 0.019). "
01/01/2004 - "First results demonstrated that the expression of cadherin-6 in renal cell carcinoma may have prognostic value. "
|2.||Kidney Neoplasms (Kidney Cancer)
01/01/2004 - "Our data suggest that cadherin-6 is a new prognostic factor for renal cancer."
07/01/1997 - "A novel cadherin transcript, cadherin-6, was recently described to be present in renal cancer cell lines and fetal kidney, but no data on protein expression nor tissue localization has been reported. "
06/01/1994 - "These results demonstrate that K-cadherin must have important functions in both the process of kidney development and tumorigenesis of some types of kidney cancer."
06/01/1994 - "The level of K-cadherin expression was also elevated in some human kidney cancer tissues. "
01/01/2005 - "In this study, we evaluated cadherin-6 mRNA as a new molecular marker for the detection of circulating renal cancer cells. "
|3.||Neoplasm Metastasis (Metastasis)
09/01/2004 - "Cadherin-6 was found in 69.9% of patients with metastases and in 34.9% of patients without apparent metastases (P = 0.0099). "
09/01/2004 - "Among 43 patients with newly diagnosed RCC, 5 of 15 patients who were positive for cadherin-6 had metastases after nephrectomy, whereas only 2 of the 28 patients with negative cadherin-6 status had recurrent disease (P = 0.0398). "
09/01/2004 - "However, subsequent metastases did not always correlate with levels of cadherin-6 mRNA. "
09/01/2004 - "The quantification of cadherin-6 mRNA in peripheral blood may be a significant predictive marker for current and future metastases. "
09/01/2004 - "Cadherin-6 mRNA levels were measured in peripheral blood samples from 66 patients with RCC, including 55 patients who had newly diagnosed RCC (43 without metastases and 12 with metastases) and 11 patients who had recurrent RCC. "
01/01/2013 - "Recently, we found Cadherin-6 (CDH6, also known as K-CAD) highly expressed in thyroid tumor cells that display mesenchymal features and aggressive phenotype, following the overexpression of the transcriptional regulator Id1. "
03/13/2012 - "Through cadherin (CDH)6 (K-cadherin), GRS bound to different ERK-activated tumor cells, and released phosphatase 2A (PP2A) from CDH6. "
01/01/2005 - "Cadherin-6 is a useful molecular marker to detect the circulating cancer cells disseminated from conventional RCC."
01/01/2004 - "We prospectively evaluated the importance of cadherin-6 in renal tumors in a large cohort of patients. "
10/01/1998 - "Hence, we have investigated the relationship between prognosis and cadherin-6 expression in tumor cells in 43 patients with RCC. "
03/01/2001 - "These included three renal-specific transporters (an ADH water channel, the anion transporters RST and ROAT1), a cell adhesion molecule (K-cadherin) and a kidney-specific protein upregulated in renal carcinoma (DD96). "
05/15/1995 - "Expression of cadherin-6 in various human normal tissues and carcinoma cells was examined by Northern blot analysis using a specific probe corresponding to the signal and precursor sequence. "
05/15/1995 - "Isolation and sequence analysis of human cadherin-6 complementary DNA for the full coding sequence and its expression in human carcinoma cells."
06/01/1994 - "Northern blot analysis revealed a high level of expression of K-cadherin mRNA in fetal rat kidney and brain, and rat kidney carcinoma with two major transcripts, 4.1 and 8.0 kilobases in size, whereas there was very weak or no expression in any organ of adult rats. "
06/01/1994 - "Isolation of complementary DNA encoding K-cadherin, a novel rat cadherin preferentially expressed in fetal kidney and kidney carcinoma."
|1.||Messenger RNA (mRNA)
|3.||Complementary DNA (cDNA)
|5.||Cell Cycle Proteins
|6.||Biological Markers (Surrogate Marker)
|9.||RNA (Ribonucleic Acid)
|10.||Proteins (Proteins, Gene)