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1,2,3,4- tetrahydro- 3- isoquinolinecarbonyl- cysteinyl- tyrosyl- tryptophyl- arginyl- threonyl- penicillamyl- threoninamide

a mu antagonist

Also Known As:

D-Tic-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2; TCTAP

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - 1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-cysteinyl-tyrosyl-tryptophyl-arginyl-threonyl-penicillamyl-threoninamide: 2

Related Diseases

1.

11/19/1991 - "The analogues examined were D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP), D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP), D-Tic-CTOP (TCTOP) and D-Tic-CTAP (TCTAP). "
05/01/1989 - "The compounds, D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Pen-Thr-NH2 (CTP), D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP), D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP), D-tetrahydroisoquinoline carboxylic acid (D-Tic)-Cys-Tyr-D-Trp-Lys-Thr-Pen-Thr-NH2 (D-Tic-CTP), D-Tic-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (D-Tic-CTOP) and D-Tic-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (D-Tic-CTAP), were tested in vitro and in vivo for agonist and antagonist potency and selectivity. "

Related Drugs and Biologics

1.	phenylalanyl- cyclo(cysteinyltyrosyl- tryptophyl- ornithyl- threonyl- penicillamine)threoninamide (CTOP)
2.	Cytidine Triphosphate (CTP)
3.	1,2,3,4-tetrahydroisoquinoline carboxylic acid