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5-(6)-carboxyfluorescein diacetate succinimidyl ester (CFSE)

a fluorescein based dye
Also Known As:
CFSE; 5-carboxyfluorescein diacetate succinimidyl ester and 6-carboxyfluorescein diacetate succinimidyl ester; CFDA-SE; CFDASE; carboxyfluorescein diacetate succinimidyl ester
Networked: 187 relevant articles (2 outcomes, 19 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Gründemann, Carsten: 4 articles (01/2020 - 01/2014)
2. Huber, Roman: 4 articles (01/2020 - 01/2014)
3. Steinborn, Carmen: 3 articles (01/2020 - 01/2017)
4. Lee, Ho-Young: 2 articles (07/2020 - 05/2016)
5. Bai, Yu: 2 articles (04/2019 - 01/2015)
6. Lu, Xuzhang: 2 articles (04/2019 - 01/2015)
7. Zhu, Zhichao: 2 articles (04/2019 - 01/2015)
8. Jiang, Xiuyun: 2 articles (01/2019 - 01/2017)
9. Pillarisetty, Venu G: 2 articles (01/2019 - 01/2017)
10. Seo, Y David: 2 articles (01/2019 - 01/2017)

Related Diseases

1. Neoplasms (Cancer)
2. Melanoma (Melanoma, Malignant)
07/25/2022 - "CFDA-SE, Annexin V-PI double staining, and PI single staining were used to investigate the mechanism of KYNU in melanoma and its effects on melanoma proliferation, apoptosis, invasion, and migration. "
07/01/2013 - "In the present study, in order to verify whether the persistence, distribution and function of effector cells can be improved by inhibiting immunosuppressive microenvironment, low-dose cyclophosphamide was previously intraperitoneally injected into melanoma-bearing C57BL/6 mice, thereafter, CFSE-labeled cytotoxic T lymphocytes were transfused intravenously, and their effective time, distributive pattern, and killing efficiency in different groups were observed by measuring the fluorescence intensity and cell cycle of cytotoxic T lymphocytes distributed in various organs, in comparison with tumor growth. "
02/29/2008 - "This method of TCRVbeta/CFSE dilution was used for the isolation of four different human lymphoma and melanoma-specific CD4(+) and CD8(+) T-cell clones reactive against defined and undefined tumor antigens. "
09/01/2009 - "Cytotoxicity on multiple myeloma and melanoma cell lines was assessed by measuring dilution of the carboxyfluorescein diacetate succinimydylester dye (CFSE). "
08/01/2013 - "Optimal staining concentration for CTL proliferation was determined by cell counting kit-8 (CCK-8) assay and killing efficiencies of CTLs or carboxyfluorescein diacetate succinimidyl ester (CFSE)-labeled melanoma antigen-specific cytotoxic T lymphocytes (CFSE-CTLs) for malignant melanoma cells in vitro were compared. "
3. Infections
4. Breast Neoplasms (Breast Cancer)
5. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
06/01/2006 - "To study the effects of supernatant derived from acute myeloid leukemia (AML) cell lines on proliferation and apoptosis of CD4(+) and CD8(+) T cell subsets and to investigate the mechanism by which AML escapes from immune recognition, lymphocytes were labeled with CFSE and were stimulated with anti-CD3 and anti-CD28 in presence or absence of supernatants from three AML cell lines (HL-60, NB4, U937). "
04/01/2019 - "We detected apoptosis and the NKG2D ligands expression in acute myeloid leukemia (AML) cells using flow cytometry and investigated the cytotoxicity of AML cells that had been co-cultured with natural killer (NK) cells using CFSE staining. "
01/01/2022 - "Abbreviations: C/EBPα: CCAAT/enhancer-binding protein α; TF: Transcription factor; AML: Acute myeloid leukemia; TAD: Transactivation domain; FS: Frameshift; NK: Natural killer; NKG2D: NK group 2, member D; NKG2D-Ls: Ligands for NKG2D; MHC: Major histocompatibility complex; MICA: MHC class I-related chain A; ULBP: UL16-binding protein; STAT3: Signal transducer and activator of transcription 3; LSD1: Lysine-specific demethylase 1; Ab: Antibody; PBMC: Peripheral blood mononuclear cell; PBS: Phosphate-buffered saline; CFSE: Carboxyfluorescein diacetate succinimidyl ester; PI: Propidium iodide; shRNA: Short hairpin RNA; ChIP: Chromatin immunoprecipitation; BM: Binding motif; HCNE: Highly conserved noncoding element; TSS: Transcription start site; HMA: Hypomethylating agent; AZA: Azacitidine/5-azacytidine; DAC: Decitabine/5-aza-29-deoxycytidine; 2-PCPA: Tranylcypromine; RBP: RNA-binding protein; MSI2: MUSASHI-2; HDACi: Inhibitor of histone deacetylases; VPA: Valproate; DNMTi: DNA methyl transferase inhibitor; SCLC: Small cell lung cancer."

Related Drugs and Biologics

1. Neoplasm Antigens (Tumor Antigens)
2. Cyclophosphamide (Cytoxan)
3. vadimezan
4. 5-(6)-carboxyfluorescein diacetate succinimidyl ester (CFSE)
5. Esters
6. 6-carboxyfluorescein (carboxyfluorescein)
7. Bromodeoxyuridine (BrdU)
8. Antigens
9. Annexin A5
10. Beryllium

Related Therapies and Procedures

1. Transplantation
2. Perioperative Period
3. Therapeutics
4. Surgical Instruments (Clip)
5. Injections