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romidepsin (FK228)

a bicyclic depsipeptide and a potent histone deacetylase inhibitor from Chromobacterium violaceum; structure in first source
Also Known As:
FK228; FR901228; FR 901228; FR-901228; istodax; L-Valine, N-(3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-, xi-lactone, cyclic (1-2)-disulfide, (S-(E))-
Networked: 291 relevant articles (29 outcomes, 91 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Bates, Susan E: 24 articles (07/2015 - 03/2002)
2. Piekarz, Richard L: 16 articles (07/2015 - 03/2002)
3. Prince, H Miles: 12 articles (07/2015 - 11/2009)
4. Figg, William D: 11 articles (08/2013 - 03/2002)
5. Nichols, Jean: 8 articles (08/2015 - 01/2009)
6. Fojo, Tito: 8 articles (07/2015 - 03/2002)
7. Steinberg, Seth M: 8 articles (07/2015 - 06/2006)
8. Robey, Robert W: 8 articles (05/2015 - 03/2002)
9. Frye, Robin: 7 articles (08/2013 - 02/2009)
10. Wright, John J: 7 articles (12/2012 - 06/2006)

Related Diseases

1. Neoplasms (Cancer)
2. Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
3. T-Cell Lymphoma (Lymphoma, T Cell)
4. Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
5. Pruritus (Itching)

Related Drugs and Biologics

1. Histone Deacetylase Inhibitors
2. romidepsin (FK228)
3. vorinostat (suberoylanilide hydroxamic acid)
4. bortezomib (Velcade)
5. decitabine (5-aza-2'-deoxycytidine)
6. Asp(5)- oxytocin (OXA)
7. gemcitabine
8. Vincristine (Oncovin)
9. Cyclophosphamide (Cytoxan)
10. docetaxel (Taxotere)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Castration
4. Stents
5. Homologous Transplantation (Allograft)